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> Protein (NX_Q2WGJ6)
Protein (NX_Q2WGJ6)
Protein
Gene SymbolKLHL38 to neXtProt (NX_Q2WGJ6)
DescriptionKelch-like protein 38
Chromosome8
Location8q24.13 (124657767 ~ 124665190) to Ensembl
Sequene Features : Isoforms 1, Variants 108, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 108 0
2014-09-19protein level
1 90 0
2014-05-27protein level
1 90 0
2014-02-25protein level
1 89 0
2013-12-09protein level
1 62 0
2013-11-01protein level
1 61 0
2013-09-12protein level
1 61 0
2013-08-17protein level
1 61 0
2013-07-15protein level
1 44 0
2013-06-11protein level
1 44 0
2013-02-12transcript level
1 19 0
2012-12-20transcript level
1 18 0
2012-10-30transcript level
1 26 0
2012-10-07transcript level
1 26 0
2012-08-24transcript level
1 22 0
2012-07-28transcript level
1 22 0
2012-06-08transcript level
1 24 0
2012-05-07transcript level
1 22 0
2012-04-10transcript level
1 22 0
2012-01-13transcript level
1 15 0
2011-12-20transcript level
1 15 0
2011-11-11transcript level
1 15 0
2011-08-23transcript level
1 15 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q2WGJ6-1
31 0 0 65497.9175
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6426443,EBI-742268 TADA2A  
  .histone H3 acetylation
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.chromatin organization
.zinc ion binding
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.chromosome
.nucleus
.PCAF complex
2 EBI-6426443,EBI-1047263 KRT38  
  .N/A .structural molecule activity .extracellular exosome
.intermediate filament
3 EBI-6426443,EBI-1052678 RGS20  
  .positive regulation of GTPase activity
.termination of G-protein coupled receptor signaling pathway
.regulation of G-protein coupled receptor protein signaling pathway
.GTPase activator activity .plasma membrane
.trans-Golgi network
.cytoplasm
.nucleus
4 EBI-6426443,EBI-352572 HSP90AB1  
  .regulation of cellular response to heat
.fibril organization
.cellular response to interleukin-4
  + 14 more...
.poly(A) RNA binding
.TPR domain binding
.nitric-oxide synthase regulator activity
  + 4 more...
.extracellular exosome
.melanosome
.membrane
  + 4 more...
5 EBI-6426443,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
6 EBI-6426443,EBI-1045155 MAGEA6  
  .N/A .N/A .N/A
7 EBI-6426443,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
8 EBI-6426443,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
9 EBI-6426443,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
10 EBI-6426443,EBI-10175863 UBE3A  
  .regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.protein K48-linked ubiquitination
.prostate gland growth
  + 13 more...
.ubiquitin protein ligase activity
.metal ion binding
.ligase activity
  + 2 more...
.cytosol
.cytoplasm
.nucleus
.proteasome complex
11 EBI-6426443,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
12 EBI-6426443,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
13 EBI-6426443,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
14 EBI-6426443,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
15 EBI-6426443,EBI-744342 NUDCD3  
  .N/A .N/A .N/A
16 EBI-6426443,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
17 EBI-6426443,EBI-10239812 TEKT5  
  .N/A .N/A .cilium
.microtubule
.cytoplasm
.nucleus
18 EBI-6426443,EBI-9089622 ZNF341  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
19 EBI-6426443,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
20 EBI-6426443,EBI-2548012 BLZF1  
  .Golgi to plasma membrane protein transport
.cell proliferation
.Golgi organization
  + 3 more...
.ubiquitin protein ligase binding
.enzyme binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.Golgi lumen
.cytoplasm
.nucleoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
heart22
Health State
TissuesTPM*
normal1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
esophagus2
heart muscle35.9
placenta1
prostate1.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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