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> Protein (NX_Q32M45)
Protein (NX_Q32M45)
Protein
Gene SymbolANO4 to neXtProt (NX_Q32M45)
DescriptionAnoctamin-4
Chromosome12
Location12q23.1 (101111304 ~ 101522419) to Ensembl
Sequene Features : Isoforms 3, Variants 205, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.chloride transmembrane transport
.calcium activated galactosylceramide scrambling
.calcium activated phosphatidylcholine scrambling
  + 4 more...
.phospholipid scramblase activity
.intracellular calcium activated chloride channel activity
.integral component of membrane
.plasma membrane
.intracellular
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
3 205 4
2014-09-19transcript level
3 143 4
2014-05-27transcript level
3 143 4
2014-02-25transcript level
3 143 4
2013-12-09transcript level
3 131 4
2013-11-01transcript level
3 120 4
2013-09-12transcript level
3 120 4
2013-08-17transcript level
3 120 4
2013-07-15transcript level
3 81 4
2013-06-11transcript level
3 81 4
2013-02-12transcript level
3 25 8
2012-12-20transcript level
3 26 8
2012-10-30transcript level
3 29 8
2012-10-07transcript level
3 29 4
2012-08-24transcript level
3 26 4
2012-07-28transcript level
3 26 4
2012-06-08transcript level
3 29 4
2012-05-07transcript level
3 11 4
2012-04-10transcript level
3 11 4
2012-01-13transcript level
3 8 4
2011-12-20transcript level
3 8 4
2011-11-11transcript level
3 8 4
2011-08-23transcript level
3 8 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q32M45-1
2 41 1 111389.3127
NX_Q32M45-2
0 41 1 107542.5262
NX_Q32M45-3
2 18 0 55682.4883
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain53
embryonic tissue9
kidney52
lung2
pituitary gland60
prostate36
skin4
testis22
uterus4
Health State
TissuesTPM*
normal27
germ cell tumor26
head and neck tumor7
kidney tumor14
Developmental Stage
TissuesTPM*
adult8
embryoid body14
fetus41
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland18.5
cerebral cortex8.2
duodenum2.5
ovary9.6
prostate7.5
salivary gland3
testis1.9
Tissues
TissuesExpression level
adrenal glandLow
cerebellumLow
cerebral cortexLow
colonLow
gallbladderLow
hippocampusLow
kidneyLow
lateral ventricleMedium
pancreasLow
placentaLow
rectumLow
soft tissue 1Low
stomach 1Low
testisMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610111, gene) Anoctamin 4; ANO4OMIM


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