Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q3B820)
Protein (NX_Q3B820)
Protein
Gene SymbolFAM161A to neXtProt (NX_Q3B820)
DescriptionProtein FAM161A
Chromosome2
Location2p15 (62051989 ~ 62081278) to Ensembl
Sequene Features : Isoforms 3, Variants 104, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 104 2
2014-09-19protein level
3 78 2
2014-05-27protein level
3 78 2
2014-02-25protein level
3 76 2
2013-12-09protein level
3 54 2
2013-11-01protein level
3 52 2
2013-09-12protein level
3 52 2
2013-08-17protein level
3 52 2
2013-07-15protein level
3 41 2
2013-06-11protein level
3 41 2
2013-02-12protein level
3 20 0
2012-12-20protein level
3 20 0
2012-10-30protein level
3 30 0
2012-10-07protein level
3 30 0
2012-08-24transcript level
3 22 0
2012-07-28transcript level
3 22 0
2012-06-08transcript level
3 25 0
2012-05-07transcript level
3 24 0
2012-04-10transcript level
3 24 0
2012-01-13transcript level
3 12 0
2011-12-20transcript level
3 12 0
2011-11-11transcript level
3 12 0
2011-08-23transcript level
3 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q3B820-1
0 25 0 76703.5863
NX_Q3B820-2
0 21 0 64794.7372
NX_Q3B820-3
1 25 0 83439.2823
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-719941,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-719941,EBI-740718 ZBTB43  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
3 EBI-719941,EBI-10176632 ZBTB14  
  .negative regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 2 more...
.cytoplasm
.nucleoplasm
.nucleus
4 EBI-719941,EBI-714135 STX11  
  .membrane fusion
.vesicle docking
.natural killer cell degranulation
  + 4 more...
.SNAP receptor activity
.SNARE binding
.SNARE complex
.integral component of membrane
.endomembrane system
  + 3 more...
5 EBI-719941,EBI-741602 TRIM37  
  .aggresome assembly
.protein autoubiquitination
.positive regulation of NF-kappaB transcription factor activity
  + 7 more...
.ubiquitin protein ligase activity
.protein homodimerization activity
.ubiquitin protein ligase binding
  + 5 more...
.perinuclear region of cytoplasm
.aggresome
.cytosol
  + 2 more...
6 EBI-719941,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
7 EBI-719941,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
8 EBI-719941,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
9 EBI-719941,EBI-1181367 CDR2  
  .N/A .N/A .cytoplasm
10 EBI-719941,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
11 EBI-719941,EBI-745426 PPFIA1  
  .negative regulation of establishment of protein localization to plasma membrane
.negative regulation of stress fiber assembly
.glutamate secretion
  + 4 more...
.signal transducer activity .presynaptic active zone
.focal adhesion
.cytosol
.cytoplasm
12 EBI-719941,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
13 EBI-719941,EBI-745305 IKZF1  
  .retina development in camera-type eye
.positive regulation of NK T cell differentiation
.Peyer's patch development
  + 17 more...
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.protein complex
.cytoplasm
.pericentric heterochromatin
.nucleus
14 EBI-719941,EBI-374900 MCM6  
  .DNA strand elongation involved in DNA replication
.DNA replication initiation
.DNA unwinding involved in DNA replication
  + 3 more...
.identical protein binding
.ATP binding
.single-stranded DNA binding
.DNA helicase activity
.MCM complex
.nucleoplasm
.nucleus
15 EBI-719941,EBI-357849 TNIP1  
  .modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of inflammatory response
  + 9 more...
.mitogen-activated protein kinase binding .cytoplasm
.nucleus
.intracellular
16 EBI-719941,EBI-2805604 KIAA0753  
  .N/A .N/A .centrosome
.cytoplasm
17 EBI-719941,EBI-2808286 CCDC57  
  .N/A .N/A .N/A
18 EBI-719941,EBI-747225 RUNDC3A  
  .small GTPase mediated signal transduction .GTPase regulator activity
.guanylate cyclase activator activity
.plasma membrane
.cytosol
19 EBI-719941,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
20 EBI-719941,EBI-1211496 BEND3  
  .N/A .N/A .N/A
21 EBI-719941,EBI-1105124 PDE4DIP  
  .cellular protein complex assembly .enzyme binding .myofibril
.centrosome
.Golgi apparatus
  + 2 more...
22 EBI-719941,EBI-2549423 HMBOX1  
  .positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleoplasm
.nucleus
23 EBI-719941,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
24 EBI-719941,EBI-724373 BEND5  
  .N/A .N/A .Golgi apparatus
25 EBI-719941,EBI-2807297 DHX32  
  .mRNA splicing, via spliceosome .poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
.mitochondrion
.cytoplasm
.spliceosomal complex
26 EBI-719941,EBI-10178410 NUTM1  
  .N/A .N/A .cytoplasm
.nucleus
27 EBI-719941,EBI-713786 PHC2  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 2 more...
.identical protein binding
.zinc ion binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 2 more...
28 EBI-719941,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
29 EBI-719941,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
30 EBI-719941,EBI-6872807 SYCE1  
  .cell division
.synaptonemal complex assembly
.N/A .central element
31 EBI-719941,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
32 EBI-719941,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
33 EBI-719941,EBI-2561090 POC5  
  .cell cycle .N/A .centriole
.centrosome
34 EBI-719941,EBI-10174653 DOCK8  
  .negative regulation of T cell apoptotic process
.memory T cell proliferation
.dendritic cell migration
  + 3 more...
.guanyl-nucleotide exchange factor activity .cell leading edge
.membrane
.cytosol
35 EBI-719941,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
36 EBI-719941,EBI-2548751 MIPOL1  
  .N/A .N/A .nucleus
37 EBI-719941,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
38 EBI-719941,EBI-10171416 CCDC136  
  .N/A .N/A .integral component of membrane
.mitochondrion
39 EBI-719941,EBI-741977 CEP63  
  .cell division
.spindle assembly
.signal transduction in response to DNA damage
  + 6 more...
.N/A .cytosol
.centriole
.centrosome
.spindle pole
40 EBI-719941,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
41 EBI-719941,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
42 EBI-719941,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
43 EBI-719941,EBI-2342111 TRIM15  
  .negative regulation of viral release from host cell
.negative regulation of intracellular transport of viral material
.positive regulation of RIG-I signaling pathway
  + 5 more...
.zinc ion binding .intracellular
44 EBI-719941,EBI-744115 CEP44  
  .N/A .N/A .midbody
.centrosome
.cytoplasm
.spindle pole
45 EBI-719941,EBI-751319 CARD9  
  .nucleotide-binding oligomerization domain containing signaling pathway
.defense response to virus
.defense response to Gram-positive bacterium
  + 17 more...
.CARD domain binding
.protein homodimerization activity
.plasma membrane
.cytosol
.cytoplasm
46 EBI-719941,EBI-749920 CALCOCO1  
  .positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
.intracellular steroid hormone receptor signaling pathway
  + 3 more...
.armadillo repeat domain binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 6 more...
.intracellular membrane-bounded organelle
.cytoplasm
.nucleus
.nuclear chromatin
47 EBI-719941,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
48 EBI-719941,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
49 EBI-719941,EBI-302355 PNMA2  
  .positive regulation of apoptotic process .N/A .nucleolus
50 EBI-719941,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
51 EBI-719941,EBI-719716 NINL  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.calcium ion binding .microtubule
.cytosol
.microtubule organizing center
52 EBI-719941,EBI-2682961 ZBTB1  
  .positive regulation of pro-T cell differentiation
.protein homooligomerization
.thymus development
  + 8 more...
.protein heterodimerization activity
.metal ion binding
.protein homodimerization activity
.DNA binding
.nuclear body
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
brain11
connective tissue6
embryonic tissue18
eye47
intestine4
liver14
lung11
muscle18
ovary19
placenta3
prostate5
skin9
testis34
trachea19
uterus8
vascular19
Health State
TissuesTPM*
normal11
adrenal tumor79
colorectal tumor8
germ cell tumor7
non-neoplasia31
ovarian tumor26
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult10
blastocyst32
fetus10
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.5
adrenal gland2.2
appendix1.4
cerebral cortex5.2
colon1.3
esophagus1.7
gallbladder2.6
heart muscle1.7
kidney3.8
lung2.2
lymph node1.6
ovary8.2
pancreas2.4
placenta1.7
prostate3
salivary gland1.1
skin2.2
small intestine1.3
spleen1.4
stomach3.1
testis20.6
thyroid gland6.7
urinary bladder2.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#606068, phenotype) Retinitis pigmentosa 28; RP28OMIM
2(*613596, gene) Family with sequence similarity 161, member a; FAM161AOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center