Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q3T906)
Protein (NX_Q3T906)
Protein
Gene SymbolGNPTAB to neXtProt (NX_Q3T906)
DescriptionN-acetylglucosamine-1-phosphotransferase subunits alpha/beta
Chromosome12
Location12q23.2 (102139275 ~ 102224716) to Ensembl
Sequene Features : Isoforms 2, Variants 154, PTMs 26 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.carbohydrate phosphorylation
.cell differentiation
.N-glycan processing to lysosome
  + 2 more...
.calcium ion binding
.UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
.integral component of membrane
.Golgi apparatus
.nucleus
.Golgi membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 154 26
2014-09-19protein level
2 134 26
2014-05-27protein level
2 134 26
2014-02-25protein level
2 130 26
2013-12-09protein level
2 104 26
2013-11-01protein level
2 98 26
2013-09-12protein level
2 98 26
2013-08-17protein level
2 98 26
2013-07-15protein level
2 69 16
2013-06-11protein level
2 69 16
2013-02-12protein level
2 44 23
2012-12-20protein level
2 42 23
2012-10-30protein level
2 46 23
2012-10-07protein level
2 46 16
2012-08-24protein level
2 39 16
2012-07-28protein level
2 39 16
2012-06-08protein level
2 41 16
2012-05-07protein level
2 41 16
2012-04-10protein level
2 41 16
2012-01-13protein level
2 24 16
2011-12-20protein level
2 24 16
2011-11-11protein level
2 24 16
2011-08-23protein level
2 19 16
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q3T906-1
35 22 0 143530.5127
NX_Q3T906-2
2 22 0 55947.0245
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1104907,EBI-10177272 ZNF250  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
2 EBI-1104907,EBI-359352 PSMA1  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.RNA binding
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.polysome
  + 7 more...
3 EBI-1104907,EBI-6658203 FAM90A1  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
4 EBI-1104907,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
5 EBI-1104907,EBI-745021 STAMBPL1  
  .N/A .metal ion binding
.metallopeptidase activity
.membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
bladder100
blood49
bone41
brain57
cervix20
connective tissue60
embryonic tissue61
esophagus49
eye14
heart11
intestine34
kidney47
larynx255
liver34
lung17
lymph node11
mammary gland52
muscle56
nerve128
ovary9
pancreas56
parathyroid48
pharynx24
placenta21
prostate26
skin75
spleen37
stomach31
testis13
thymus150
thyroid42
trachea77
uterus38
vascular96
Health State
TissuesTPM*
normal45
bladder carcinoma56
breast (mammary gland) tumor85
cervical tumor28
chondrosarcoma48
colorectal tumor35
esophageal tumor57
gastrointestinal tumor42
germ cell tumor37
glioma65
head and neck tumor44
kidney tumor14
leukemia52
liver tumor20
non-neoplasia20
ovarian tumor13
pancreatic tumor95
primitive neuroectodermal tumor of the CNS15
prostate cancer9
retinoblastoma21
skin tumor47
soft tissue/muscle tissue tumor71
uterine tumor77
Developmental Stage
TissuesTPM*
adult44
embryoid body42
blastocyst113
neonate32
fetus52
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.8
adrenal gland9.6
appendix18
bone marrow13.9
cerebral cortex24.2
colon34.4
duodenum14.8
esophagus17.8
gallbladder18.1
heart muscle20.5
kidney16.2
liver6.2
lung25.8
lymph node20.5
ovary8.1
pancreas5.7
placenta13.7
prostate19
salivary gland42.9
skin19.3
small intestine14.4
spleen17.6
stomach21.7
testis12.1
thyroid gland13.3
urinary bladder24.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#252500, phenotype) Mucolipidosis ii alpha/betaOMIM
2(#252600, phenotype) Mucolipidosis iii alpha/betaOMIM
3(*607840, gene) N-acetylglucosamine-1-phosphotransferase, alpha/beta subunits; GNPTABOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center