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> Protein (NX_Q496Y0)
Protein (NX_Q496Y0)
Protein
Gene SymbolLONRF3 to neXtProt (NX_Q496Y0)
DescriptionLON peptidase N-terminal domain and RING finger protein 3
ChromosomeX
LocationXq24 (118108581 ~ 118152318) to Ensembl
Sequene Features : Isoforms 3, Variants 81, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .zinc ion binding
.ATP-dependent peptidase activity
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 81 0
2014-09-19protein level
3 61 0
2014-05-27protein level
3 61 0
2014-02-25protein level
3 61 0
2013-12-09protein level
3 57 0
2013-11-01protein level
3 56 0
2013-09-12protein level
3 56 0
2013-08-17protein level
3 56 0
2013-07-15protein level
3 37 0
2013-06-11protein level
3 37 0
2013-02-12protein level
3 12 0
2012-12-20protein level
3 12 0
2012-10-30protein level
3 13 0
2012-10-07protein level
3 13 0
2012-08-24protein level
3 12 0
2012-07-28protein level
3 12 0
2012-06-08protein level
3 10 0
2012-05-07protein level
3 10 0
2012-04-10protein level
3 10 0
2012-01-13protein level
3 3 0
2011-12-20protein level
3 3 0
2011-11-11protein level
3 3 0
2011-08-23protein level
3 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q496Y0-1
0 36 0 84434.9256
NX_Q496Y0-2
0 34 0 79777.4797
NX_Q496Y0-3
0 28 0 67165.2325
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2690768,EBI-354213 PHB  
  .negative regulation of glucocorticoid receptor signaling pathway
.positive regulation of protein stabilization
.DNA biosynthetic process
  + 20 more...
.transcription regulatory region DNA binding
.histone deacetylase binding
.proteinase activated receptor binding
  + 4 more...
.extracellular exosome
.membrane
.cell surface
  + 8 more...
2 EBI-2690768,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
3 EBI-2690768,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
brain13
cervix20
intestine21
kidney9
liver4
lung20
mammary gland6
mouth15
pancreas4
testis4
thyroid42
uterus4
Health State
TissuesTPM*
normal8
colorectal tumor17
head and neck tumor22
liver tumor10
lung tumor9
Developmental Stage
TissuesTPM*
adult5
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.7
adrenal gland3.3
appendix2.3
bone marrow2.1
cerebral cortex1.2
colon3.7
duodenum2.1
esophagus1.4
gallbladder2.4
kidney2.6
liver8.5
lung5.5
ovary1.5
pancreas3.2
prostate1.5
salivary gland3.7
small intestine1.9
stomach4.1
testis2.2
thyroid gland6.8
urinary bladder1.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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