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> Protein (NX_Q4ZIN3)
Protein (NX_Q4ZIN3)
Protein
Gene SymbolTMEM259 to neXtProt (NX_Q4ZIN3)
DescriptionMembralin
Chromosome19
Location19p13.3 (1009647 ~ 1021117) to Ensembl
Sequene Features : Isoforms 2, Variants 17, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .integral component of membrane
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 17 3
2014-09-19protein level
2 31 3
2014-05-27protein level
2 30 3
2014-02-25protein level
2 31 2
2013-12-09protein level
2 21 2
2013-11-01protein level
2 19 2
2013-09-12protein level
2 19 2
2013-08-17protein level
2 19 2
2013-07-15protein level
2 12 1
2013-06-11protein level
2 12 1
2013-02-12protein level
2 9 2
2012-12-20protein level
2 10 2
2012-10-30protein level
2 12 2
2012-10-07protein level
2 12 1
2012-08-24protein level
2 10 1
2012-07-28protein level
2 10 1
2012-06-08protein level
2 10 1
2012-05-07protein level
2 10 1
2012-04-10protein level
2 10 1
2012-01-13protein level
2 3 1
2011-12-20protein level
2 3 1
2011-11-11protein level
2 3 1
2011-08-23protein level
2 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q4ZIN3-1
4 18 0 67844.8394
NX_Q4ZIN3-2
0 18 0 46400.3871
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites150
bladder66
blood81
bone97
brain68
cervix103
connective tissue20
embryonic tissue164
eye90
heart178
intestine133
kidney185
larynx255
liver38
lung122
lymph293
lymph node311
mammary gland72
mouth30
muscle75
nerve128
ovary167
pancreas140
parathyroid437
pharynx49
pituitary gland60
placenta49
prostate158
salivary gland98
skin99
spleen149
stomach146
testis80
thymus25
thyroid64
tonsil117
uterus47
vascular19
Health State
TissuesTPM*
normal89
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor75
cervical tumor57
chondrosarcoma120
colorectal tumor106
gastrointestinal tumor194
germ cell tumor37
glioma158
head and neck tumor74
kidney tumor72
leukemia381
liver tumor83
lung tumor97
lymphoma180
non-neoplasia20
ovarian tumor105
pancreatic tumor123
primitive neuroectodermal tumor of the CNS94
prostate cancer260
retinoblastoma64
skin tumor103
soft tissue/muscle tissue tumor39
uterine tumor77
Developmental Stage
TissuesTPM*
adult93
embryoid body142
blastocyst195
fetus82
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue65.5
adrenal gland63.4
appendix77.3
bone marrow81.8
cerebral cortex41.4
colon50.9
duodenum64.9
esophagus52.1
gallbladder70.4
heart muscle69.3
kidney50
liver28.9
lung75.5
lymph node98.5
ovary55
pancreas57.8
placenta61.9
prostate65.9
salivary gland73.9
skin119.6
small intestine63.9
spleen120.6
stomach78.5
testis70
thyroid gland66.1
urinary bladder63.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611011, gene) Chromosome 19 open reading frame 6; C19ORF6OMIM


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