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> Protein (NX_Q53F39)
Protein (NX_Q53F39)
Protein
Gene SymbolMPPE1 to neXtProt (NX_Q53F39)
DescriptionMetallophosphoesterase 1
Chromosome18
Location18p11.21 (11882621 ~ 11909222) to Ensembl
Sequene Features : Isoforms 5, Variants 49, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ER to Golgi vesicle-mediated transport
.GPI anchor biosynthetic process
.GPI anchor binding
.manganese ion binding
.phosphoric diester hydrolase activity
.endoplasmic reticulum exit site
.endoplasmic reticulum-Golgi intermediate compartment membrane
.integral component of membrane
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 49 1
2014-09-19protein level
5 45 1
2014-05-27protein level
5 45 1
2014-02-25protein level
5 45 1
2013-12-09protein level
5 33 1
2013-11-01protein level
5 33 1
2013-09-12protein level
5 33 1
2013-08-17protein level
5 33 1
2013-07-15protein level
5 23 0
2013-06-11protein level
5 23 0
2013-02-12protein level
5 17 0
2012-12-20protein level
5 16 0
2012-10-30protein level
5 19 0
2012-10-07protein level
5 19 0
2012-08-24protein level
5 18 0
2012-07-28protein level
5 18 0
2012-06-08protein level
5 18 0
2012-05-07protein level
5 18 0
2012-04-10protein level
5 18 0
2012-01-13protein level
5 18 0
2011-12-20protein level
5 18 0
2011-11-11protein level
5 18 0
2011-08-23protein level
5 18 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q53F39-1
0 17 0 45111.8732
NX_Q53F39-2
0 16 0 38907.4145
NX_Q53F39-3
0 16 0 39035.4727
NX_Q53F39-4
1 13 0 38245.5246
NX_Q53F39-5
2 9 0 29331.829
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10242229,EBI-743265 ZNF426  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
bladder33
blood24
bone13
bone marrow20
brain33
cervix41
connective tissue13
esophagus49
eye4
intestine17
kidney18
lung17
lymph22
mammary gland6
mouth15
prostate5
skin4
spleen74
testis2
thymus25
trachea57
uterus8
Health State
TissuesTPM*
normal11
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma36
esophageal tumor57
germ cell tumor11
glioma9
head and neck tumor7
kidney tumor14
lung tumor19
lymphoma13
non-neoplasia20
retinoblastoma21
Developmental Stage
TissuesTPM*
adult33
fetus39
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.1
adrenal gland20.4
appendix26.9
bone marrow22.7
cerebral cortex17.6
colon26.8
duodenum24.9
esophagus18
gallbladder25.7
heart muscle16.9
kidney32
liver18.5
lung36.8
lymph node24.6
ovary17.6
pancreas17
placenta17.6
prostate23.2
salivary gland15.1
skin29.9
small intestine27.3
spleen25.2
stomach29.6
testis14.1
thyroid gland49.5
urinary bladder22.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611900, gene) Metallophosphoesterase 1; MPPE1OMIM


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