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> Protein (NX_Q53HC0)
Protein (NX_Q53HC0)
Protein
Gene SymbolCCDC92 to neXtProt (NX_Q53HC0)
DescriptionCoiled-coil domain-containing protein 92
Chromosome12
Location12q24.31 (124403207 ~ 124457378) to Ensembl
Sequene Features : Isoforms 2, Variants 43, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .centriole
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 43 2
2014-09-19protein level
1 27 2
2014-05-27protein level
1 27 2
2014-02-25protein level
1 27 2
2013-12-09protein level
1 15 2
2013-11-01protein level
1 15 2
2013-09-12protein level
1 15 2
2013-08-17protein level
1 15 2
2013-07-15protein level
1 11 2
2013-06-11protein level
1 11 2
2013-02-12protein level
1 8 1
2012-12-20protein level
1 8 1
2012-10-30protein level
1 9 1
2012-10-07protein level
1 9 1
2012-08-24transcript level
1 7 1
2012-07-28transcript level
1 7 1
2012-06-08transcript level
1 7 1
2012-05-07transcript level
1 7 1
2012-04-10transcript level
1 7 1
2012-01-13transcript level
1 6 1
2011-12-20transcript level
1 6 1
2011-11-11transcript level
1 6 1
2011-08-23transcript level
1 6 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q53HC0-1
1 16 0 36938.1991
NX_Q53HC0-2
1 16 0 35088.4209
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-719994,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-719994,EBI-10175039 TP53BP2  
  .positive regulation of execution phase of apoptosis
.intrinsic apoptotic signaling pathway by p53 class mediator
.negative regulation of cell cycle
  + 7 more...
.NF-kappaB binding
.identical protein binding
.SH3/SH2 adaptor activity
.p53 binding
.perinuclear region of cytoplasm
.cytoplasm
.nucleus
3 EBI-719994,EBI-701903 FHL2  
  .heart trabecula formation
.ventricular cardiac muscle cell development
.atrial cardiac muscle cell development
  + 9 more...
.androgen receptor binding
.identical protein binding
.zinc ion binding
  + 2 more...
.M band
.Z disc
.actin cytoskeleton
  + 3 more...
4 EBI-719994,EBI-742887 CEP76  
  .regulation of centriole replication
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .protein complex
.cytosol
.centriole
.centrosome
5 EBI-719994,EBI-3937015 CEP164  
  .cell division
.cilium assembly
.mitotic nuclear division
  + 4 more...
.N/A .ciliary transition fiber
.cytosol
.centriole
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland91
blood40
bone41
brain85
cervix20
connective tissue40
embryonic tissue9
eye47
heart55
intestine38
kidney42
liver4
lung47
lymph node44
mammary gland39
muscle9
nerve64
ovary49
pancreas60
parathyroid48
pharynx24
pituitary gland242
placenta60
prostate31
salivary gland98
skin47
stomach10
testis165
uterus30
vascular38
Health State
TissuesTPM*
normal48
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma72
colorectal tumor53
gastrointestinal tumor8
germ cell tumor3
glioma74
head and neck tumor29
kidney tumor58
leukemia74
liver tumor10
lung tumor48
lymphoma41
non-neoplasia51
ovarian tumor65
pancreatic tumor76
primitive neuroectodermal tumor of the CNS39
prostate cancer9
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult45
embryoid body28
fetus43
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue35.4
adrenal gland16.6
appendix17.2
bone marrow3.6
cerebral cortex51.6
colon13.3
duodenum17.6
esophagus13.3
gallbladder18.4
heart muscle33.4
kidney22.1
liver10.7
lung28.4
lymph node13.8
ovary18.4
pancreas7.4
placenta19.5
prostate18.5
salivary gland12.7
skin6.9
small intestine17.7
spleen17.2
stomach13.7
testis51.5
thyroid gland21.9
urinary bladder18.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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