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> Protein (NX_Q5HYK7)
Protein (NX_Q5HYK7)
Protein
Gene SymbolSH3D19 to neXtProt (NX_Q5HYK7)
DescriptionSH3 domain-containing protein 19
Chromosome4
Location4q31.3 (152023903 ~ 152246784) to Ensembl
Sequene Features : Isoforms 5, Variants 89, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane organization
.positive regulation of membrane protein ectodomain proteolysis
.regulation of cell morphogenesis
  + 2 more...
.proline-rich region binding .plasma membrane
.cytosol
.Golgi apparatus
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 89 2
2014-09-19protein level
5 71 2
2014-05-27protein level
5 71 2
2014-02-25protein level
5 71 2
2013-12-09protein level
5 55 2
2013-11-01protein level
5 54 2
2013-09-12protein level
5 54 2
2013-08-17protein level
5 54 2
2013-07-15protein level
5 33 2
2013-06-11protein level
5 33 2
2013-02-12protein level
5 21 13
2012-12-20protein level
5 18 13
2012-10-30protein level
5 25 13
2012-10-07protein level
5 25 3
2012-08-24protein level
5 19 3
2012-07-28protein level
5 19 3
2012-06-08protein level
5 22 3
2012-05-07protein level
5 22 3
2012-04-10protein level
5 22 3
2012-01-13protein level
5 9 3
2011-12-20protein level
5 9 3
2011-11-11protein level
5 9 3
2011-08-23protein level
5 9 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5HYK7-1
0 39 0 86471.484
NX_Q5HYK7-2
0 38 0 84083.3164
NX_Q5HYK7-3
1 35 0 80081.0568
NX_Q5HYK7-4
0 20 0 47026.5026
NX_Q5HYK7-5
0 19 0 44638.335
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2563437,EBI-722667 SH3YL1  
  .regulation of ruffle assembly
.phosphatidylinositol biosynthetic process
.phosphatidylinositol binding
.phosphatase binding
.ruffle membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites50
bladder33
bone41
bone marrow41
brain23
cervix41
connective tissue60
embryonic tissue61
eye38
intestine129
kidney23
liver43
lung41
mammary gland125
mouth15
muscle18
nerve64
ovary29
pancreas28
pharynx49
placenta63
prostate47
salivary gland49
skin18
stomach83
testis43
thymus37
thyroid107
trachea154
umbilical cord72
uterus103
vascular19
Health State
TissuesTPM*
normal42
bladder carcinoma56
breast (mammary gland) tumor75
cervical tumor57
chondrosarcoma132
colorectal tumor159
gastrointestinal tumor59
germ cell tumor18
glioma9
head and neck tumor29
kidney tumor14
liver tumor52
lung tumor19
non-neoplasia31
ovarian tumor39
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer67
skin tumor15
soft tissue/muscle tissue tumor39
uterine tumor22
Developmental Stage
TissuesTPM*
adult65
embryoid body71
blastocyst16
neonate32
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue76.6
adrenal gland19.8
appendix16.4
cerebral cortex11.1
colon56.6
duodenum45.2
esophagus41.1
gallbladder79.4
heart muscle54.8
kidney27.7
liver31.6
lung43.1
lymph node7.1
ovary46.1
pancreas7.3
placenta31.5
prostate27.5
salivary gland13.1
skin37
small intestine50.8
spleen8.1
stomach29.4
testis17.2
thyroid gland29
urinary bladder46.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608674, gene) Sh3 domain protein 19OMIM


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