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> Protein (NX_Q5JR59)
Protein (NX_Q5JR59)
Protein
Gene SymbolMTUS2 to neXtProt (NX_Q5JR59)
DescriptionMicrotubule-associated tumor suppressor candidate 2
Chromosome13
Location13q12.3 (29598748 ~ 30077892) to Ensembl
Sequene Features : Isoforms 3, Variants 286, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 286 0
2014-09-19protein level
3 201 0
2014-05-27protein level
3 201 0
2014-02-25protein level
3 200 0
2013-12-09protein level
3 154 0
2013-11-01protein level
3 153 0
2013-09-12protein level
3 153 0
2013-08-17protein level
3 153 0
2013-07-15protein level
3 100 0
2013-06-11protein level
3 100 0
2013-02-12protein level
3 42 0
2012-12-20protein level
3 39 0
2012-10-30protein level
3 56 0
2012-10-07protein level
3 56 0
2012-08-24protein level
3 49 0
2012-07-28protein level
3 49 0
2012-06-08protein level
3 50 0
2012-05-07protein level
3 31 0
2012-04-10protein level
3 31 0
2012-01-13protein level
3 15 0
2011-12-20protein level
3 15 0
2011-11-11protein level
3 15 0
2011-08-23protein level
3 15 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5JR59-2
51 18 0 150102.6408
NX_Q5JR59-3
2 18 0 40720.4438
NX_Q5JR59-4
0 14 0 30045.2475
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-742948,EBI-10173222 DCDC2B  
  .intracellular signal transduction .N/A .N/A
2 EBI-742948,EBI-5453796 GTPBP10  
  .ribosome biogenesis .poly(A) RNA binding
.GTP binding
.GTPase activity
.magnesium ion binding
.mitochondrion
.nucleolus
.chromosome
3 EBI-742948,EBI-3925400 ZNF785  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
4 EBI-742948,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
5 EBI-742948,EBI-2871971 CXCL11  
  .chemokine-mediated signaling pathway
.positive regulation of release of sequestered calcium ion into cytosol
.positive regulation of cAMP-mediated signaling
  + 11 more...
.CXCR3 chemokine receptor binding
.heparin binding
.chemokine activity
.extracellular space
.extracellular region
6 EBI-742948,EBI-1210440 ZSCAN12  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
7 EBI-742948,EBI-740402 DTNB  
  .N/A .zinc ion binding .synapse
.cytoplasm
8 EBI-742948,EBI-743272 USP2  
  .regulation of proteasomal protein catabolic process
.protein stabilization
.positive regulation of skeletal muscle tissue development
  + 11 more...
.metal ion binding
.ubiquitin protein ligase binding
.cyclin binding
  + 2 more...
.perinuclear region of cytoplasm
.cell cortex
.centrosome
  + 2 more...
9 EBI-742948,EBI-749295 STK16  
  .cellular response to transforming growth factor beta stimulus
.protein autophosphorylation
.regulation of signal transduction
.ATP binding
.non-membrane spanning protein tyrosine kinase activity
.protein serine/threonine kinase activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.perinuclear region of cytoplasm
.membrane
.Golgi-associated vesicle
.cytoplasm
10 EBI-742948,EBI-1215612 FCHSD2  
  .N/A .N/A .N/A
11 EBI-742948,EBI-7543896 SCEL  
  .keratinocyte differentiation
.embryo development
.epidermis development
.zinc ion binding .extracellular exosome
.cytoplasm
.cornified envelope
12 EBI-742948,EBI-1045459 SNAI1  
  .regulation of tight junction assembly
.negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
.Notch signaling involved in heart development
  + 16 more...
.metal ion binding
.kinase binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
.RNA polymerase II regulatory region sequence-specific DNA binding
.cytoplasm
.nucleus
13 EBI-742948,EBI-1053651 SNRPB2  
  .gene expression
.RNA splicing
.mRNA processing
  + 2 more...
.snRNA binding
.nucleotide binding
.catalytic step 2 spliceosome
.nucleolus
.U2 snRNP
  + 2 more...
14 EBI-742948,EBI-346340 HCK  
  .positive regulation of actin cytoskeleton reorganization
.regulation of podosome assembly
.cellular response to peptide hormone stimulus
  + 28 more...
.ATP binding
.receptor binding
.non-membrane spanning protein tyrosine kinase activity
.protein tyrosine kinase activity
.cell projection
.extrinsic component of cytoplasmic side of plasma membrane
.transport vesicle
  + 7 more...
15 EBI-742948,EBI-607085 SNRPA  
  .gene expression
.RNA splicing
.mRNA splicing, via spliceosome
.poly(A) RNA binding
.snRNA binding
.RNA binding
.nucleotide binding
.cytoplasm
.nucleolus
.U1 snRNP
  + 2 more...
16 EBI-742948,EBI-356254 SLC25A6  
  .regulation of insulin secretion
.active induction of host immune response by virus
.small molecule metabolic process
  + 9 more...
.ATP:ADP antiporter activity .integral component of membrane
.mitochondrial inner membrane presequence translocase complex
.mitochondrial inner membrane
  + 2 more...
17 EBI-742948,EBI-10177272 ZNF250  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
18 EBI-742948,EBI-717634 ZNF20  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
19 EBI-742948,EBI-1640965 ZNF3  
  .leukocyte activation
.cell differentiation
.multicellular organismal development
  + 2 more...
.identical protein binding
.zinc ion binding
.DNA binding
.nucleus
20 EBI-742948,EBI-348444 NELFE  
  .negative regulation of mRNA polyadenylation
.positive regulation of viral transcription
.negative regulation of transcription elongation from RNA polymerase II promoter
  + 4 more...
.poly(A) RNA binding
.RNA binding
.nucleotide binding
.NELF complex
.mitochondrion
.nucleoplasm
.nucleus
21 EBI-742948,EBI-359352 PSMA1  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.RNA binding
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.polysome
  + 7 more...
22 EBI-742948,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
23 EBI-742948,EBI-621389 RPA1  
  .regulation of cellular response to heat
.error-free translesion synthesis
.homeostasis of number of cells within a tissue
  + 31 more...
.metal ion binding
.single-stranded DNA binding
.damaged DNA binding
.chromatin binding
.PML body
.DNA replication factor A complex
.nucleoplasm
  + 3 more...
24 EBI-742948,EBI-745213 AQP1  
  .cation transmembrane transport
.maintenance of symbiont-containing vacuole by host
.ammonium transmembrane transport
  + 60 more...
.carbon dioxide transmembrane transporter activity
.nitric oxide transmembrane transporter activity
.transmembrane transporter activity
  + 8 more...
.extracellular exosome
.apical part of cell
.axon terminus
  + 12 more...
25 EBI-742948,EBI-358122 RPL9  
  .cellular protein metabolic process
.viral transcription
.viral life cycle
  + 8 more...
.rRNA binding
.structural constituent of ribosome
.RNA binding
.cytosolic large ribosomal subunit
.membrane
.focal adhesion
  + 5 more...
26 EBI-742948,EBI-712388 RGS2  
  .regulation of adrenergic receptor signaling pathway
.positive regulation of cardiac muscle contraction
.relaxation of vascular smooth muscle
  + 13 more...
.calmodulin binding
.GTPase activator activity
.neuron projection
.cytoplasmic side of plasma membrane
.plasma membrane
  + 5 more...
27 EBI-742948,EBI-10182930 MAGEA8  
  .N/A .N/A .N/A
28 EBI-742948,EBI-749129 ZNF136  
  .transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription corepressor activity
.DNA binding
.nucleus
29 EBI-742948,EBI-1048159 MFAP1  
  .extracellular matrix organization .poly(A) RNA binding .extracellular region
.microfibril
30 EBI-742948,EBI-308629 HDAC4  
  .histone H4 deacetylation
.histone H3 deacetylation
.response to interleukin-1
  + 29 more...
.NAD-dependent histone deacetylase activity (H3-K18 specific)
.repressing transcription factor binding
.NAD-dependent histone deacetylase activity (H4-K16 specific)
  + 12 more...
.actomyosin
.A band
.neuromuscular junction
  + 7 more...
31 EBI-742948,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
32 EBI-742948,EBI-10223348 HSF2  
  .positive regulation of transcription from RNA polymerase II promoter
.spermatogenesis
.transcription from RNA polymerase II promoter
.transcription coactivator activity
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
  + 2 more...
.cytoplasm
.nucleus
33 EBI-742948,EBI-746238 CDK18  
  .N/A .ATP binding
.cyclin-dependent protein serine/threonine kinase activity
.N/A
34 EBI-742948,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
35 EBI-742948,EBI-10225757 ZNF844  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
36 EBI-742948,EBI-10226171 ZNF415  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.microtubule cytoskeleton
.cytoplasm
.nucleolus
37 EBI-742948,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
.cytosol
  + 4 more...
38 EBI-742948,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
39 EBI-742948,EBI-632715 SNW1  
  .cellular response to retinoic acid
.positive regulation of vitamin D receptor signaling pathway
.regulation of vitamin D receptor signaling pathway
  + 19 more...
.SMAD binding
.poly(A) RNA binding
.retinoic acid receptor binding
  + 5 more...
.catalytic step 2 spliceosome
.nuclear matrix
.spliceosomal complex
  + 3 more...
40 EBI-742948,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
41 EBI-742948,EBI-10233912 COG2  
  .oligosaccharide biosynthetic process
.Golgi organization
.intra-Golgi vesicle-mediated transport
  + 2 more...
.protein transporter activity .Golgi transport complex
.cytosol
.Golgi stack
.Golgi membrane
42 EBI-742948,EBI-10234557 ODF1  
  .cell differentiation
.spermatogenesis
.multicellular organismal development
.N/A .nucleus
.outer dense fiber
43 EBI-742948,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
44 EBI-742948,EBI-746189 CDK5R1  
  .positive regulation of protein targeting to membrane
.positive regulation of protein serine/threonine kinase activity
.positive regulation of cell cycle arrest
  + 28 more...
.cadherin binding
.protein serine/threonine kinase activator activity
.protein kinase binding
  + 5 more...
.perinuclear region of cytoplasm
.contractile fiber
.intracellular membrane-bounded organelle
  + 14 more...
45 EBI-742948,EBI-748280 DLGAP5  
  .positive regulation of mitotic metaphase/anaphase transition
.signaling
.dephosphorylation
  + 2 more...
.phosphoprotein phosphatase activity .spindle pole centrosome
.microtubule organizing center
.cytoplasm
.nucleus
46 EBI-742948,EBI-1026992 TAF13  
  .viral process
.gene expression
.transcription elongation from RNA polymerase II promoter
  + 4 more...
.protein C-terminus binding
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleolus
.transcription factor TFIID complex
.nucleoplasm
.nucleus
47 EBI-742948,EBI-1004115 MAPRE1  
  .positive regulation of microtubule plus-end binding
.cell division
.protein localization to microtubule
  + 7 more...
.microtubule plus-end binding
.poly(A) RNA binding
.protein C-terminus binding
.microtubule plus-end
.cell projection membrane
.cortical microtubule cytoskeleton
  + 6 more...
48 EBI-742948,EBI-3920053 ZSCAN26  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.nucleic acid binding
.nucleus
49 EBI-742948,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
50 EBI-742948,EBI-10241197 TSGA10IP  
  .N/A .N/A .N/A
51 EBI-742948,EBI-2212355 CRY2  
  .negative regulation of glucocorticoid secretion
.negative regulation of glucocorticoid receptor signaling pathway
.regulation of sodium-dependent phosphate transport
  + 16 more...
.FAD binding
.ubiquitin binding
.phosphatase binding
  + 7 more...
.mitochondrion
.cytoplasm
.nucleus
.extracellular region
52 EBI-742948,EBI-740767 ZC2HC1C  
  .N/A .metal ion binding .N/A
53 EBI-742948,EBI-739879 ALS2CR11  
  .N/A .N/A .N/A
54 EBI-742948,EBI-10246152 SYT6  
  .acrosomal vesicle exocytosis
.calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
  + 2 more...
.protein homodimerization activity
.clathrin binding
.syntaxin binding
.calcium ion binding
.perinuclear endoplasmic reticulum
.synaptic vesicle membrane
.cell junction
  + 4 more...
55 EBI-742948,EBI-10247271 FAM74A6  
  .N/A .N/A .N/A
56 EBI-742948,EBI-1105124 PDE4DIP  
  .cellular protein complex assembly .enzyme binding .myofibril
.centrosome
.Golgi apparatus
  + 2 more...
57 EBI-742948,EBI-2557469 PPP1R18  
  .N/A .N/A .cytoskeleton
.cytoplasm
58 EBI-742948,EBI-930143 CDC73  
  .negative regulation of G1/S transition of mitotic cell cycle
.cellular response to lipopolysaccharide
.negative regulation of epithelial cell proliferation
  + 17 more...
.RNA polymerase II core binding .Cdc73/Paf1 complex
.nucleoplasm
.nucleus
59 EBI-742948,EBI-8635958 SPATA8  
  .N/A .N/A .N/A
60 EBI-742948,EBI-7236323 ZFP2  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
61 EBI-742948,EBI-10257016 ZNF572  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
62 EBI-742948,EBI-10257651 LIMS2  
  .positive regulation of integrin-mediated signaling pathway
.negative regulation of hepatocyte proliferation
.negative regulation of neural precursor cell proliferation
  + 4 more...
.zinc ion binding .focal adhesion
.plasma membrane
.cytosol
.nucleus
63 EBI-742948,EBI-10258233 CATIP  
  .cilium organization
.actin filament polymerization
.calmodulin binding .actin cytoskeleton
.plasma membrane
.cytoplasm
.nucleus
64 EBI-742948,EBI-7233259 ZNF329  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
65 EBI-742948,EBI-720304 ZNF410  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
66 EBI-742948,EBI-10260504 CDC20B  
  .N/A .N/A .N/A
67 EBI-742948,EBI-6658203 FAM90A1  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
68 EBI-742948,EBI-3919850 CDKL3  
  .dendrite extension
.positive regulation of dendrite morphogenesis
.negative regulation of axon extension
.cellular protein modification process
.ATP binding
.cyclin-dependent protein serine/threonine kinase activity
.protein kinase activity
.cytoplasm
.nucleus
69 EBI-742948,EBI-10262147 CCDC60  
  .N/A .N/A .N/A
70 EBI-742948,EBI-10247802 CCDC146  
  .N/A .N/A .centriole
71 EBI-742948,EBI-726439 ZNF440  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
72 EBI-742948,EBI-744311 CCDC116  
  .N/A .N/A .centrosome
73 EBI-742948,EBI-1104570 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
74 EBI-742948,EBI-747580 ZNF439  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
75 EBI-742948,EBI-751248 FAM13C  
  .N/A .N/A .N/A
76 EBI-742948,EBI-744545 CATSPER1  
  .membrane depolarization during action potential
.calcium ion import
.regulation of cilium beat frequency involved in ciliary motility
  + 9 more...
.voltage-gated calcium channel activity
.calcium activated cation channel activity
.CatSper complex
.motile cilium
.plasma membrane
77 EBI-742948,EBI-474076 PPHLN1  
  .keratinization .poly(A) RNA binding .intracellular membrane-bounded organelle
.Golgi apparatus
.cytoplasm
.nucleoplasm
78 EBI-742948,EBI-726826 NUDT10  
  .small molecule metabolic process
.inositol phosphate metabolic process
.inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
.inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
.inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
  + 6 more...
.cytosol
79 EBI-742948,EBI-747505 C1orf216  
  .N/A .N/A .N/A
80 EBI-742948,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
81 EBI-742948,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
82 EBI-742948,EBI-743796 RAB3IL1  
  .positive regulation of GTPase activity
.protein transport
.Rab guanyl-nucleotide exchange factor activity .N/A
83 EBI-742948,EBI-10274247 CERK  
  .lipid phosphorylation
.small molecule metabolic process
.protein kinase C-activating G-protein coupled receptor signaling pathway
  + 3 more...
.ATP binding
.diacylglycerol kinase activity
.NAD+ kinase activity
  + 2 more...
.integral component of membrane
.plasma membrane
.mitochondrion
84 EBI-742948,EBI-746325 RHPN1  
  .regulation of catalytic activity
.small GTPase mediated signal transduction
.N/A .cytosol
85 EBI-742948,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
86 EBI-742948,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
87 EBI-742948,EBI-7199479 PTPMT1  
  .inositol phosphate dephosphorylation
.glycerophospholipid biosynthetic process
.small molecule metabolic process
  + 4 more...
.phosphatidylglycerophosphatase activity
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
.integral component of mitochondrial inner membrane
.mitochondrion
.nucleus
88 EBI-742948,EBI-10277687 SELM  
  .N/A .N/A .perinuclear region of cytoplasm
.Golgi apparatus
.endoplasmic reticulum
  + 2 more...
89 EBI-742948,EBI-448771 DOCK2  
  .positive regulation of phagocytosis
.regulation of defense response to virus by virus
.alpha-beta T cell proliferation
  + 12 more...
.T cell receptor binding
.Rac guanyl-nucleotide exchange factor activity
.extracellular exosome
.membrane
.endomembrane system
  + 2 more...
90 EBI-742948,EBI-399080 KAT5  
  .positive regulation of protein acetylation
.cellular response to estradiol stimulus
.positive regulation of transcription from RNA polymerase II promoter
  + 14 more...
.repressing transcription factor binding
.androgen receptor binding
.metal ion binding
  + 2 more...
.perinuclear region of cytoplasm
.NuA4 histone acetyltransferase complex
.Piccolo NuA4 histone acetyltransferase complex
  + 6 more...
91 EBI-742948,EBI-455078 SMARCE1  
  .negative regulation of transcription, DNA-templated
.ATP-dependent chromatin remodeling
.metabolic process
  + 4 more...
.protein N-terminus binding
.ligand-dependent nuclear receptor binding
.N-acetyltransferase activity
  + 4 more...
.nBAF complex
.npBAF complex
.protein complex
  + 6 more...
92 EBI-742948,EBI-726510 LENG1  
  .N/A .N/A .N/A
93 EBI-742948,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
94 EBI-742948,EBI-372775 CEP95  
  .N/A .N/A .centrosome
.cytoplasm
.spindle pole
95 EBI-742948,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
.nucleus
96 EBI-742948,EBI-2510106 LRR1  
  .protein ubiquitination .N/A .N/A
97 EBI-742948,EBI-719840 CCDC17  
  .N/A .N/A .N/A
98 EBI-742948,EBI-2682299 ZMAT2  
  .N/A .zinc ion binding
.DNA binding
.nucleus
99 EBI-742948,EBI-8653994 ZNF599  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
100 EBI-742948,EBI-739588 TP53RK  
  .threonylcarbamoyladenosine metabolic process
.tRNA processing
.protein phosphorylation
.hydrolase activity
.ATP binding
.protein serine/threonine kinase activity
.p53 binding
.membrane
.cytosol
.nucleus
.EKC/KEOPS complex
101 EBI-742948,EBI-10293291 LYSMD1  
  .N/A .N/A .N/A
102 EBI-742948,EBI-747175 ZNF607  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
103 EBI-742948,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
104 EBI-742948,EBI-1642317 KIF2C  
  .regulation of chromosome segregation
.cell division
.establishment or maintenance of microtubule cytoskeleton polarity
  + 10 more...
.microtubule plus-end binding
.centromeric DNA binding
.ATPase activity
  + 2 more...
.microtubule plus-end
.membrane
.microtubule cytoskeleton
  + 5 more...
105 EBI-742948,EBI-2932492 TXN2  
  .oxidation-reduction process
.response to axon injury
.cell redox homeostasis
  + 12 more...
.peptide-methionine (R)-S-oxide reductase activity
.oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
.protein disulfide oxidoreductase activity
.peptide-methionine (S)-S-oxide reductase activity
.neuronal cell body
.dendrite
.mitochondrial matrix
  + 2 more...
106 EBI-742948,EBI-702235 PKP2  
  .regulation of tight junction assembly
.regulation of ventricular cardiac muscle cell action potential
.establishment of protein localization to plasma membrane
  + 19 more...
.cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
.alpha-catenin binding
.ion channel binding
  + 4 more...
.desmosome
.cell junction
.integral component of membrane
  + 7 more...
107 EBI-742948,EBI-2849569 ZFYVE21  
  .N/A .metal ion binding .cytoplasmic membrane-bounded vesicle
.focal adhesion
.endosome
108 EBI-742948,EBI-745276 ZNF670  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
109 EBI-742948,EBI-741350 THAP7  
  .negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.C2H2 zinc finger domain binding
.protein N-terminus binding
.metal ion binding
.DNA binding
.nuclear speck
.chromosome
110 EBI-742948,EBI-749118 WAC  
  .histone H2B conserved C-terminal lysine ubiquitination
.positive regulation of transcription, DNA-templated
.G1 DNA damage checkpoint
  + 5 more...
.chromatin binding
.RNA polymerase II core binding
.nuclear speck
.spliceosomal complex
.nucleoplasm
.nucleus
111 EBI-742948,EBI-743265 ZNF426  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
112 EBI-742948,EBI-744935 C20orf195  
  .N/A .N/A .extracellular exosome
113 EBI-742948,EBI-10303449 SETD5  
  .N/A .N/A .N/A
114 EBI-742948,EBI-928842 NDEL1  
  .neuron projection extension
.neurofilament cytoskeleton organization
.centrosome localization
  + 20 more...
.oligopeptidase activity
.microtubule binding
.neurofilament cytoskeleton
.axon hillock
.cell leading edge
  + 10 more...
115 EBI-742948,EBI-1050793 SLIRP  
  .mitochondrion morphogenesis
.sperm motility
.single fertilization
  + 4 more...
.poly(A) RNA binding
.nucleotide binding
.perinuclear region of cytoplasm
.sperm flagellum
.ribonucleoprotein complex
  + 3 more...
116 EBI-742948,EBI-10306373 GAL3ST2  
  .biosynthetic process .sulfotransferase activity
.galactosylceramide sulfotransferase activity
.Golgi cisterna membrane
.integral component of membrane
.membrane
117 EBI-742948,EBI-747035 SH2D4A  
  .negative regulation of phosphatase activity .phosphatase binding .cytoplasm
118 EBI-742948,EBI-712912 CBX8  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 3 more...
.methylated histone binding
.ubiquitin-protein transferase activity
.single-stranded RNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 3 more...
119 EBI-742948,EBI-9679045 DMRT3  
  .male sex differentiation
.regulation of odontogenesis of dentin-containing tooth
.ventral spinal cord interneuron specification
  + 4 more...
.protein heterodimerization activity
.metal ion binding
.protein homodimerization activity
  + 2 more...
.nucleus
120 EBI-742948,EBI-769257 PLSCR4  
  .cellular response to lipopolysaccharide
.phospholipid scrambling
.CD4 receptor binding
.enzyme binding
.phospholipid scramblase activity
.calcium ion binding
.extracellular exosome
.integral component of membrane
.plasma membrane
121 EBI-742948,EBI-10313866 C19orf66  
  .N/A .N/A .N/A
122 EBI-742948,EBI-719816 FBXO34  
  .N/A .N/A .cytoplasm
.nucleoplasm
123 EBI-742948,EBI-8643161 C1orf109  
  .N/A .N/A .N/A
124 EBI-742948,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
125 EBI-742948,EBI-9116427 ZNF624  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
126 EBI-742948,EBI-8636823 CTSZ  
  .epithelial tube branching involved in lung morphogenesis
.proteolysis involved in cellular protein catabolic process
.cellular protein metabolic process
  + 2 more...
.cysteine-type peptidase activity
.cysteine-type endopeptidase activity
.extracellular exosome
.intracellular membrane-bounded organelle
.plasma membrane
  + 3 more...
127 EBI-742948,EBI-10249760 NDOR1  
  .oxidation-reduction process
.small molecule metabolic process
.cellular response to menadione
  + 2 more...
.NADP binding
.flavin adenine dinucleotide binding
.oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
  + 4 more...
.perinuclear region of cytoplasm
.intermediate filament cytoskeleton
.cytosol
  + 2 more...
128 EBI-742948,EBI-395282 AFF4  
  .spermatid development
.transcription from RNA polymerase II promoter
.sequence-specific DNA binding transcription factor activity .transcriptionally active chromatin
.transcription elongation factor complex
.mitochondrion
  + 3 more...
129 EBI-742948,EBI-1759386 SLC23A1  
  .transepithelial L-ascorbic acid transport
.dehydroascorbic acid transport
.small molecule metabolic process
  + 12 more...
.sodium-dependent L-ascorbate transmembrane transporter activity
.dehydroascorbic acid transporter activity
.L-ascorbic acid transporter activity
  + 3 more...
.extracellular exosome
.intracellular organelle
.apical plasma membrane
  + 6 more...
130 EBI-742948,EBI-2134033 DCTN4  
  .antigen processing and presentation of exogenous peptide antigen via MHC class II
.nuclear migration
.protein N-terminus binding .dynactin complex
.cytoplasmic dynein complex
.cytosol
  + 3 more...
131 EBI-742948,EBI-1105370 ZNF490  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
132 EBI-742948,EBI-749023 ZNF232  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
133 EBI-742948,EBI-717201 SPG7  
  .anterograde axon cargo transport
.nervous system development
.mitochondrion organization
.proteolysis
.unfolded protein binding
.zinc ion binding
.peptidase activity
  + 2 more...
.mitochondrial membrane
.integral component of membrane
.mitochondrion
134 EBI-742948,EBI-766064 MTMR6  
  .potassium ion transmembrane transport
.phosphatidylinositol dephosphorylation
.small molecule metabolic process
  + 4 more...
.phosphatidylinositol phosphate phosphatase activity
.calcium-activated potassium channel activity
.protein tyrosine phosphatase activity
.protein serine/threonine phosphatase activity
.cytosol
.cytoplasm
.nuclear envelope
135 EBI-742948,EBI-713000 POLDIP2  
  .mitochondrion morphogenesis .DNA binding .mitochondrial nucleoid
.mitochondrion
.nucleus
136 EBI-742948,EBI-714987 ZNF337  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain15
connective tissue6
eye19
heart78
intestine4
liver4
lung20
muscle18
ovary9
pancreas14
testis6
trachea19
Health State
TissuesTPM*
normal12
colorectal tumor8
non-neoplasia10
pancreatic tumor28
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult4
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
cerebral cortex2.7
heart muscle41.3
ovary8.2
pancreas7.2
testis1.9
urinary bladder3.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusLow
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandLow
placentaMedium
prostateLow
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandLow
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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