Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q5PSV4)
Protein (NX_Q5PSV4)
Protein
Gene SymbolBRMS1L to neXtProt (NX_Q5PSV4)
DescriptionBreast cancer metastasis-suppressor 1-like protein
Chromosome14
Location14q13.2 (36295524 ~ 36401531) to Ensembl
Sequene Features : Isoforms 2, Variants 35, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of growth
.histone deacetylation
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.histone deacetylase binding .Sin3-type complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 35 1
2014-09-19protein level
2 24 1
2014-05-27protein level
1 24 1
2014-02-25protein level
1 24 1
2013-12-09protein level
1 22 1
2013-11-01protein level
1 22 0
2013-09-12protein level
1 22 0
2013-08-17protein level
1 22 0
2013-07-15protein level
1 12 0
2013-06-11protein level
1 12 0
2013-02-12protein level
1 4 0
2012-12-20protein level
1 4 0
2012-10-30protein level
1 4 0
2012-10-07protein level
1 4 0
2012-08-24protein level
1 4 0
2012-07-28protein level
1 4 0
2012-06-08protein level
1 5 0
2012-05-07protein level
1 4 0
2012-04-10protein level
1 4 0
2012-01-13protein level
1 4 0
2011-12-20protein level
1 4 0
2011-11-11protein level
1 4 0
2011-08-23protein level
1 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5PSV4-1
1 13 0 37605.3555
NX_Q5PSV4-2
1 13 0 32324.2816
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5666615,EBI-77797 ACTN2  
  .negative regulation of protein localization to cell surface
.positive regulation of potassium ion transmembrane transporter activity
.negative regulation of potassium ion transmembrane transporter activity
  + 13 more...
.titin Z domain binding
.FATZ binding
.protein dimerization activity
  + 8 more...
.extracellular exosome
.dendritic spine
.pseudopodium
  + 9 more...
2 EBI-5666615,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
3 EBI-5666615,EBI-10187270 AMOTL2  
  .hippo signaling
.Wnt signaling pathway
.N/A .recycling endosome
.cytoplasmic vesicle
.apical plasma membrane
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
brain30
cervix20
connective tissue6
embryonic tissue28
eye28
heart22
kidney4
liver4
lung23
lymph node22
mammary gland6
muscle37
nerve64
ovary9
parathyroid48
placenta10
prostate10
skin18
testis11
uterus21
vascular19
Health State
TissuesTPM*
normal23
bladder carcinoma56
breast (mammary gland) tumor10
cervical tumor28
germ cell tumor26
glioma9
kidney tumor14
leukemia10
lung tumor9
non-neoplasia10
ovarian tumor13
primitive neuroectodermal tumor of the CNS7
prostate cancer9
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor39
uterine tumor11
Developmental Stage
TissuesTPM*
adult13
embryoid body14
blastocyst32
neonate96
fetus53
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.2
adrenal gland12.4
appendix5.2
bone marrow4.1
cerebral cortex16.3
colon4.4
duodenum4.4
esophagus7.2
gallbladder7.4
heart muscle9.7
kidney8.9
liver3.8
lung5.6
lymph node4.1
ovary8.4
pancreas1.5
placenta7.5
prostate7.4
salivary gland3.3
skin7
small intestine3.3
spleen4.2
stomach4.4
testis7.4
thyroid gland7.9
urinary bladder6.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center