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> Protein (NX_Q5R372)
Protein (NX_Q5R372)
Protein
Gene SymbolRABGAP1L to neXtProt (NX_Q5R372)
DescriptionRab GTPase-activating protein 1-like
Chromosome1
Location1q25.1 (174128548 ~ 174964445) to Ensembl
Sequene Features : Isoforms 9, Variants 115, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of GTPase activity
.regulation of protein localization
.Rab GTPase binding
.GTPase activator activity
.Golgi apparatus
.early endosome
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
9 115 6
2014-09-19protein level
9 91 6
2014-05-27protein level
9 91 6
2014-02-25protein level
9 91 6
2013-12-09protein level
9 69 6
2013-11-01protein level
9 64 6
2013-09-12protein level
9 64 6
2013-08-17protein level
9 64 6
2013-07-15protein level
9 45 5
2013-06-11protein level
9 45 5
2013-02-12protein level
9 18 18
2012-12-20protein level
9 18 18
2012-10-30protein level
9 20 18
2012-10-07protein level
9 20 5
2012-08-24protein level
9 17 5
2012-07-28protein level
9 16 5
2012-06-08protein level
9 2 5
2012-05-07protein level
9 2 5
2012-04-10protein level
9 2 5
2012-01-13protein level
9 2 5
2011-12-20protein level
9 2 5
2011-11-11protein level
9 2 4
2011-08-23protein level
9 2 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5R372-1
0 34 1 92453.6105
NX_Q5R372-2
2 22 0 67959.6987
NX_Q5R372-3
1 33 1 93941.4604
NX_Q5R372-4
1 33 1 90780.0147
NX_Q5R372-5
1 4 12 43860.5477
NX_Q5R372-6
1 4 12 43732.4532
NX_Q5R372-7
1 4 12 41518.4428
NX_Q5R372-8
4 3 12 42661.9471
NX_Q5R372-9
1 1 0 8661.2666
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10692254,EBI-8475192 MECOM  
  .regulation of transcription, DNA-templated .sequence-specific DNA binding transcription factor activity .N/A
2 EBI-10692254,EBI-10694291 C9orf43  
  .N/A .N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder133
blood81
bone13
bone marrow20
brain39
connective tissue20
ear124
embryonic tissue28
esophagus99
eye28
heart11
intestine30
kidney33
larynx42
liver19
lung23
lymph180
lymph node122
mammary gland19
mouth15
muscle37
nerve64
pancreas37
parathyroid48
pharynx49
pituitary gland181
placenta77
prostate5
spleen37
stomach31
testis22
thymus12
thyroid42
tonsil470
trachea57
uterus8
vascular19
Health State
TissuesTPM*
normal26
bladder carcinoma56
breast (mammary gland) tumor10
chondrosarcoma24
colorectal tumor8
gastrointestinal tumor16
germ cell tumor18
head and neck tumor22
leukemia31
lymphoma110
non-neoplasia31
prostate cancer19
soft tissue/muscle tissue tumor119
uterine tumor33
Developmental Stage
TissuesTPM*
adult40
embryoid body28
blastocyst48
fetus44
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.7
adrenal gland10.6
appendix25.1
bone marrow23.3
cerebral cortex24.9
colon22.1
duodenum21.6
esophagus29.1
gallbladder33.3
heart muscle154.5
kidney16.2
liver10.9
lung30.9
lymph node63
ovary33.3
pancreas10.5
placenta22.7
prostate11.2
salivary gland19.5
skin18
small intestine24.1
spleen24.4
stomach25.4
testis36.7
thyroid gland13.4
urinary bladder40.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609238, gene) Rab gtpase-activating protein 1-like; RABGAP1LOMIM


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