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> Protein (NX_Q5SQN1)
Protein (NX_Q5SQN1)
Protein
Gene SymbolSNAP47 to neXtProt (NX_Q5SQN1)
DescriptionSynaptosomal-associated protein 47
Chromosome1
Location1q42.13 (227916240 ~ 227968927) to Ensembl
Sequene Features : Isoforms 4, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.long-term synaptic potentiation
.synaptic vesicle fusion to presynaptic membrane
.synaptic vesicle priming
.syntaxin binding
.SNAP receptor activity
.perinuclear region of cytoplasm
.neuronal cell body
.SNARE complex
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 65 0
2014-09-19protein level
4 54 0
2014-05-27protein level
4 54 0
2014-02-25protein level
4 54 0
2013-12-09protein level
4 40 0
2013-11-01protein level
4 38 0
2013-09-12protein level
4 38 0
2013-08-17protein level
4 38 0
2013-07-15protein level
4 32 0
2013-06-11protein level
4 32 0
2013-02-12protein level
4 22 0
2012-12-20protein level
4 22 0
2012-10-30protein level
4 22 0
2012-10-07protein level
4 22 0
2012-08-24protein level
4 22 0
2012-07-28protein level
4 22 0
2012-06-08protein level
4 24 0
2012-05-07protein level
4 20 0
2012-04-10protein level
4 20 0
2012-01-13protein level
4 12 0
2011-12-20protein level
4 12 0
2011-11-11protein level
4 12 0
2011-08-23transcript level
4 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5SQN1-1
0 27 0 52529.0531
NX_Q5SQN1-2
0 25 0 50393.8177
NX_Q5SQN1-3
0 10 0 22628.6031
NX_Q5SQN1-4
0 12 0 24763.8385
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10244848,EBI-1045155 MAGEA6  
  .N/A .N/A .N/A
2 EBI-10244848,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
3 EBI-10244848,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
4 EBI-10244848,EBI-1643885 KLC3  
  .axon cargo transport .microtubule motor activity .neuron projection
.ciliary rootlet
.motile cilium
  + 3 more...
5 EBI-10244848,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
6 EBI-10244848,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
7 EBI-10244848,EBI-743099 FATE1  
  .N/A .N/A .integral component of membrane
.endoplasmic reticulum
8 EBI-10244848,EBI-413317 SPAG5  
  .regulation of attachment of spindle microtubules to kinetochore
.cell division
.chromosome segregation
  + 2 more...
.N/A .mitotic spindle
.microtubule plus-end
.midbody
  + 7 more...
9 EBI-10244848,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood49
bone13
brain31
cervix123
connective tissue33
embryonic tissue37
eye86
heart33
intestine17
kidney52
liver58
lung41
lymph22
lymph node22
mammary gland13
muscle9
nerve64
ovary88
pancreas60
pituitary gland60
placenta42
prostate36
salivary gland49
skin42
spleen18
stomach10
testis39
thymus12
thyroid42
tonsil58
uterus56
Health State
TissuesTPM*
normal29
breast (mammary gland) tumor21
cervical tumor86
chondrosarcoma48
colorectal tumor8
gastrointestinal tumor25
germ cell tumor30
glioma93
head and neck tumor22
kidney tumor101
leukemia42
liver tumor104
lung tumor68
lymphoma27
non-neoplasia20
ovarian tumor65
pancreatic tumor85
primitive neuroectodermal tumor of the CNS78
prostate cancer57
retinoblastoma150
skin tumor31
soft tissue/muscle tissue tumor87
Developmental Stage
TissuesTPM*
adult33
embryoid body28
blastocyst65
fetus23
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.7
adrenal gland31.8
appendix12
bone marrow6.2
cerebral cortex28.3
colon11.2
duodenum9.3
esophagus12.8
gallbladder13.9
heart muscle39
kidney17.9
liver13.1
lung13.6
lymph node18.9
ovary40.1
pancreas9.1
placenta19.2
prostate15.9
salivary gland16.3
skin12.3
small intestine10
spleen11.8
stomach11.1
testis36.4
thyroid gland21.9
urinary bladder17.1
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
breastHigh
bronchusHigh
cerebellumLow
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumMedium
endometrium 1High
endometrium 2High
epididymisMedium
esophagusHigh
fallopian tubeHigh
gallbladderHigh
hippocampusLow
kidneyHigh
lateral ventricleLow
liverHigh
lungMedium
lymph nodeLow
nasopharynxHigh
oral mucosaHigh
ovaryLow
pancreasLow
parathyroid glandLow
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleMedium
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1High
soft tissue 2High
spleenLow
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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