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> Protein (NX_Q5SXH7)
Protein (NX_Q5SXH7)
Protein
Gene SymbolPLEKHS1 to neXtProt (NX_Q5SXH7)
DescriptionPleckstrin homology domain-containing family S member 1
Chromosome10
Location10q25.3 (115511213 ~ 115543188) to Ensembl
Sequene Features : Isoforms 5, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 52 0
2014-09-19protein level
5 49 0
2014-05-27protein level
5 49 0
2014-02-25protein level
5 31 0
2013-12-09protein level
5 25 0
2013-11-01protein level
5 22 0
2013-09-12protein level
5 22 0
2013-08-17protein level
5 22 0
2013-07-15transcript level
5 24 0
2013-06-11transcript level
5 24 0
2013-02-12protein level
5 13 5
2012-12-20protein level
5 14 5
2012-10-30protein level
5 16 5
2012-10-07protein level
5 16 1
2012-08-24protein level
5 15 1
2012-07-28protein level
5 15 1
2012-06-08protein level
5 2 1
2012-05-07protein level
5 2 1
2012-04-10protein level
5 2 1
2012-01-13protein level
5 2 1
2011-12-20protein level
5 2 1
2011-11-11protein level
5 2 1
2011-08-23protein level
5 2 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5SXH7-1
0 22 0 51806.3806
NX_Q5SXH7-2
0 22 0 50367.5454
NX_Q5SXH7-3
0 18 0 40971.9524
NX_Q5SXH7-4
0 18 0 40956.821
NX_Q5SXH7-5
4 20 0 52502.2105
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10691507,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
2 EBI-10691507,EBI-79893 PIK3R3  
  .phosphatidylinositol phosphorylation
.small molecule metabolic process
.regulation of phosphatidylinositol 3-kinase activity
  + 4 more...
.1-phosphatidylinositol-3-kinase regulator activity
.1-phosphatidylinositol-3-kinase activity
.phosphatidylinositol 3-kinase complex
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
eye4
intestine17
liver9
lung41
mammary gland46
mouth30
ovary9
pharynx49
stomach10
testis9
trachea617
uterus38
Health State
TissuesTPM*
normal6
breast (mammary gland) tumor53
head and neck tumor14
ovarian tumor13
uterine tumor77
Developmental Stage
TissuesTPM*
adult9
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix4.9
colon3.3
duodenum33.7
gallbladder2
lung5.3
pancreas12.9
prostate4.4
salivary gland40.1
small intestine30.9
stomach8.1
testis1.4
urinary bladder2.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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