Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q5T124)
Protein (NX_Q5T124)
Protein
Gene SymbolUBXN11 to neXtProt (NX_Q5T124)
DescriptionUBX domain-containing protein 11
Chromosome1
Location1p36.11 (26607819 ~ 26644854) to Ensembl
Sequene Features : Isoforms 8, Variants 86, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.proteasome-mediated ubiquitin-dependent protein catabolic process .ubiquitin binding .cytoskeleton
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
8 86 0
2014-09-19protein level
8 73 0
2014-05-27transcript level
8 73 0
2014-02-25transcript level
8 73 0
2013-12-09transcript level
8 49 0
2013-11-01transcript level
8 47 0
2013-09-12transcript level
8 47 0
2013-08-17transcript level
8 47 0
2013-07-15transcript level
8 36 0
2013-06-11transcript level
8 36 0
2013-02-12transcript level
8 28 0
2012-12-20transcript level
8 26 0
2012-10-30transcript level
8 32 0
2012-10-07transcript level
8 32 0
2012-08-24transcript level
8 27 0
2012-07-28transcript level
8 23 0
2012-06-08transcript level
8 29 0
2012-05-07transcript level
8 29 0
2012-04-10transcript level
8 29 0
2012-01-13transcript level
8 25 0
2011-12-20transcript level
8 25 0
2011-11-11transcript level
8 25 0
2011-08-23transcript level
8 25 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5T124-1
0 26 0 57336.7709
NX_Q5T124-2
0 24 0 53941.2844
NX_Q5T124-3
1 18 0 43244.9051
NX_Q5T124-4
1 23 0 53157.6625
NX_Q5T124-5
0 8 0 22176.364
NX_Q5T124-6
0 19 0 36278.784
NX_Q5T124-7
0 17 0 32883.2975
NX_Q5T124-8
0 21 0 49413.9498
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-746004,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
2 EBI-746004,EBI-398610 EIF4E2  
  .cytokine-mediated signaling pathway
.negative regulation of translation
.in utero embryonic development
.poly(A) RNA binding
.ubiquitin protein ligase binding
.translation factor activity, RNA binding
  + 2 more...
.mRNA cap binding complex
.cytosol
3 EBI-746004,EBI-2367123 RHOBTB3  
  .retrograde transport, endosome to Golgi
.metabolic process
.small GTPase mediated signal transduction
.Rab GTPase binding
.ATPase activity
.GTP binding
.ATP binding
.extracellular exosome
.Golgi apparatus
4 EBI-746004,EBI-73440 EIF4E  
  .positive regulation of mitotic cell cycle
.cellular protein metabolic process
.lung development
  + 11 more...
.poly(A) RNA binding
.translation initiation factor activity
.RNA cap binding
.extracellular exosome
.chromatoid body
.RISC complex
  + 6 more...
5 EBI-746004,EBI-359352 PSMA1  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.RNA binding
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.polysome
  + 7 more...
6 EBI-746004,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
7 EBI-746004,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
8 EBI-746004,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
.cytosol
  + 4 more...
9 EBI-746004,EBI-10248548 RNF213  
  .protein autoubiquitination
.protein ubiquitination
.ATPase activity
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.membrane
.cytoplasm
.nucleolus
10 EBI-746004,EBI-749051 C6orf165  
  .N/A .N/A .N/A
11 EBI-746004,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
12 EBI-746004,EBI-748391 SCNM1  
  .RNA splicing
.mRNA processing
.metal ion binding
.enzyme binding
.nuclear speck
.nucleolus
.nucleus
13 EBI-746004,EBI-744099 ENKD1  
  .N/A .N/A .microtubule cytoskeleton
.cytoplasmic microtubule
14 EBI-746004,EBI-747035 SH2D4A  
  .negative regulation of phosphatase activity .phosphatase binding .cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder100
blood57
bone69
bone marrow20
brain53
cervix123
connective tissue20
embryonic tissue37
eye28
heart22
intestine38
kidney42
liver34
lung59
lymph45
lymph node55
mammary gland46
mouth30
muscle9
ovary59
pancreas37
pituitary gland121
placenta31
prostate52
skin28
spleen243
stomach41
testis128
thymus150
thyroid42
trachea38
uterus30
vascular19
Health State
TissuesTPM*
normal59
bladder carcinoma56
breast (mammary gland) tumor64
chondrosarcoma36
colorectal tumor8
gastrointestinal tumor16
germ cell tumor37
glioma18
head and neck tumor14
kidney tumor43
leukemia84
liver tumor41
lung tumor29
lymphoma124
non-neoplasia41
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS7
prostate cancer19
retinoblastoma43
soft tissue/muscle tissue tumor31
uterine tumor11
Developmental Stage
TissuesTPM*
adult41
embryoid body28
blastocyst65
fetus25
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.2
adrenal gland11.6
appendix24.1
bone marrow32.9
cerebral cortex10.1
colon7.9
duodenum9.1
esophagus6.5
gallbladder14.7
heart muscle7.8
kidney15.5
liver5.4
lung26.6
lymph node21.9
ovary17
pancreas6.4
placenta8.9
prostate11.5
salivary gland10.9
skin14.9
small intestine8.6
spleen28.7
stomach11.4
testis36.5
thyroid gland30.2
urinary bladder11.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609151, gene) SociusOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center