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> Protein (NX_Q5T8I9)
Protein (NX_Q5T8I9)
Protein
Gene SymbolHENMT1 to neXtProt (NX_Q5T8I9)
DescriptionSmall RNA 2'-O-methyltransferase
Chromosome1
Location1p13.3 (109190912 ~ 109204148) to Ensembl
Sequene Features : Isoforms 1, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.piRNA metabolic process
.gene silencing by RNA
.gene expression
.RNA methylation
.metal ion binding
.RNA methyltransferase activity
.O-methyltransferase activity
.RNA binding
.P granule
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 52 5
2014-09-19protein level
1 41 5
2014-05-27protein level
1 41 5
2014-02-25protein level
1 41 5
2013-12-09protein level
1 32 5
2013-11-01protein level
1 32 5
2013-09-12protein level
1 32 5
2013-08-17protein level
1 32 5
2013-07-15protein level
1 20 0
2013-06-11protein level
1 20 0
2013-02-12protein level
1 15 0
2012-12-20protein level
1 15 0
2012-10-30protein level
1 16 0
2012-10-07protein level
1 16 0
2012-08-24transcript level
1 11 0
2012-07-28transcript level
1 11 0
2012-06-08transcript level
1 13 0
2012-05-07transcript level
1 13 0
2012-04-10transcript level
1 13 0
2012-01-13transcript level
1 9 0
2011-12-20transcript level
1 9 0
2011-11-11transcript level
1 9 0
2011-08-23transcript level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5T8I9-1
19 0 0 44496.3041
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-9675710,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood40
bone marrow41
brain34
cervix82
connective tissue13
esophagus49
eye9
intestine21
liver4
lung2
lymph45
lymph node33
mammary gland6
mouth30
ovary9
pancreas28
pharynx49
placenta3
prostate42
skin37
spleen37
stomach31
testis126
thymus25
uterus12
vascular19
Health State
TissuesTPM*
normal29
cervical tumor115
colorectal tumor35
esophageal tumor57
gastrointestinal tumor25
germ cell tumor64
glioma9
head and neck tumor14
leukemia21
liver tumor10
lymphoma27
non-neoplasia10
pancreatic tumor28
prostate cancer57
skin tumor63
uterine tumor22
Developmental Stage
TissuesTPM*
adult18
fetus26
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.7
adrenal gland3.3
appendix8.9
bone marrow8.2
cerebral cortex9
colon7.3
duodenum4.3
esophagus3.3
gallbladder7
heart muscle1.5
kidney2.1
lung4.2
lymph node13.5
ovary5
pancreas1.1
placenta4.8
prostate3.7
salivary gland1.7
skin3.2
small intestine7.2
spleen8.8
stomach4.9
testis69.2
thyroid gland1.9
urinary bladder10.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612178, gene) Chromosome 1 open reading frame 59; C1ORF59OMIM


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