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> Protein (NX_Q5VVH5)
Protein (NX_Q5VVH5)
Protein
Gene SymbolIRAK1BP1 to neXtProt (NX_Q5VVH5)
DescriptionInterleukin-1 receptor-associated kinase 1-binding protein 1
Chromosome6
Location6q14.1 (79577189 ~ 79656157) to Ensembl
Sequene Features : Isoforms 1, Variants 41, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.I-kappaB kinase/NF-kappaB signaling
.immune response
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 41 6
2014-09-19protein level
1 33 6
2014-05-27transcript level
1 33 6
2014-02-25transcript level
1 33 6
2013-12-09transcript level
1 24 6
2013-11-01transcript level
1 24 6
2013-09-12transcript level
1 24 6
2013-08-17transcript level
1 24 6
2013-07-15transcript level
1 20 6
2013-06-11transcript level
1 20 6
2013-02-12transcript level
1 9 6
2012-12-20transcript level
1 8 6
2012-10-30transcript level
1 12 6
2012-10-07transcript level
1 12 6
2012-08-24transcript level
1 12 6
2012-07-28transcript level
1 12 6
2012-06-08transcript level
1 12 6
2012-05-07transcript level
1 11 6
2012-04-10transcript level
1 11 6
2012-01-13transcript level
1 4 6
2011-12-20transcript level
1 4 6
2011-11-11transcript level
1 4 6
2011-08-23transcript level
1 4 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5VVH5-1
14 0 0 29087.9778
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-9658404,EBI-717422 TFCP2  
  .regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.protein C-terminus binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
bone13
brain9
eye14
intestine12
kidney14
liver4
lung5
mammary gland6
muscle28
ovary19
pancreas18
parathyroid48
skin4
stomach31
testis22
Health State
TissuesTPM*
normal10
germ cell tumor11
glioma18
kidney tumor14
lung tumor9
ovarian tumor13
primitive neuroectodermal tumor of the CNS47
retinoblastoma43
skin tumor7
Developmental Stage
TissuesTPM*
adult8
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.1
adrenal gland1.8
cerebral cortex1.7
colon1.6
duodenum1.1
esophagus1.4
gallbladder1.5
heart muscle1.3
kidney2.8
lung2.5
lymph node1
ovary3.4
pancreas1.1
prostate2.1
salivary gland2.4
skin1.3
small intestine1.5
spleen1.6
stomach2.1
testis4.9
thyroid gland3.9
urinary bladder1.9
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowLow
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusLow
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
pancreasHigh
parathyroid glandLow
placentaMedium
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Low
soft tissue 2Medium
spleenLow
stomach 1High
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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