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> Protein (NX_Q5VWN6)
Protein (NX_Q5VWN6)
Protein
Gene SymbolFAM208B to neXtProt (NX_Q5VWN6)
DescriptionProtein FAM208B
Chromosome10
Location10p15.1 (5726801 ~ 5805703) to Ensembl
Sequene Features : Isoforms 2, Variants 108, PTMs 17 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 108 17
2014-09-19protein level
2 220 17
2014-05-27protein level
2 220 17
2014-02-25protein level
2 218 17
2013-12-09protein level
2 156 17
2013-11-01protein level
2 150 15
2013-09-12protein level
2 150 15
2013-08-17protein level
2 150 15
2013-07-15protein level
2 102 15
2013-06-11protein level
2 102 15
2013-02-12protein level
2 57 21
2012-12-20protein level
2 50 21
2012-10-30protein level
2 89 21
2012-10-07protein level
2 89 14
2012-08-24protein level
2 85 14
2012-07-28protein level
2 84 14
2012-06-08protein level
2 89 14
2012-05-07protein level
2 79 14
2012-04-10protein level
2 79 14
2012-01-13protein level
2 47 14
2011-12-20protein level
2 47 14
2011-11-11protein level
2 47 9
2011-08-23protein level
2 47 9
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q5VWN6-1
40 71 0 268674.5764
NX_Q5VWN6-2
0 71 0 180266.7681
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10172380,EBI-954338 SCAMP1  
  .protein transport
.endocytosis
.post-Golgi vesicle-mediated transport
.exocytosis
.N/A .recycling endosome membrane
.zymogen granule membrane
.synaptic vesicle membrane
  + 3 more...
2 EBI-10172380,EBI-1055079 POLR1C  
  .negative regulation of gene expression, epigenetic
.innate immune response
.regulation of gene expression, epigenetic
  + 9 more...
.DNA-directed RNA polymerase activity
.DNA binding
.cytosol
.DNA-directed RNA polymerase I complex
.DNA-directed RNA polymerase III complex
.nucleoplasm
3 EBI-10172380,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
4 EBI-10172380,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
5 EBI-10172380,EBI-8639312 LMO1  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding .nucleus
6 EBI-10172380,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
7 EBI-10172380,EBI-711389 ERH  
  .positive regulation of Notch signaling pathway
.cell cycle
.pyrimidine nucleotide biosynthetic process
  + 3 more...
.poly(A) RNA binding .midbody
.membrane
8 EBI-10172380,EBI-9675802 MORN3  
  .N/A .N/A .nucleus
9 EBI-10172380,EBI-4397613 KCTD9  
  .protein homooligomerization .N/A .N/A
10 EBI-10172380,EBI-10244131 FBF1  
  .establishment of epithelial cell polarity
.apical junction assembly
.cilium assembly
.organelle organization
.N/A .ciliary transition fiber
.cell junction
.cytosol
  + 3 more...
11 EBI-10172380,EBI-747353 ATRIP  
  .DNA repair
.DNA replication
.DNA damage checkpoint
.K63-linked polyubiquitin binding .nucleoplasm
.nucleus
12 EBI-10172380,EBI-10293968 PPP1R16B  
  .positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
.negative regulation of peptidyl-serine dephosphorylation
.establishment of endothelial barrier
  + 6 more...
.protein phosphatase type 1 regulator activity .perinuclear region of cytoplasm
.cell projection
.plasma membrane
.nucleus
13 EBI-10172380,EBI-751319 CARD9  
  .nucleotide-binding oligomerization domain containing signaling pathway
.defense response to virus
.defense response to Gram-positive bacterium
  + 17 more...
.CARD domain binding
.protein homodimerization activity
.plasma membrane
.cytosol
.cytoplasm
14 EBI-10172380,EBI-740364 NEK6  
  .regulation of cellular senescence
.spindle assembly
.protein autophosphorylation
  + 13 more...
.protein kinase binding
.kinesin binding
.ATP binding
  + 3 more...
.nuclear speck
.microtubule
.cytosol
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder66
blood32
bone41
bone marrow61
brain24
cervix41
connective tissue33
ear62
embryonic tissue75
eye52
intestine51
kidney23
liver82
lung26
lymph22
lymph node155
mammary gland72
mouth45
muscle56
pancreas42
pituitary gland60
placenta35
prostate21
skin42
spleen18
stomach41
testis68
thymus50
thyroid42
tonsil58
trachea38
uterus17
vascular135
Health State
TissuesTPM*
normal48
breast (mammary gland) tumor53
cervical tumor57
chondrosarcoma48
colorectal tumor79
gastrointestinal tumor33
germ cell tumor34
head and neck tumor37
leukemia74
liver tumor135
lung tumor38
lymphoma27
non-neoplasia20
pancreatic tumor38
primitive neuroectodermal tumor of the CNS15
prostate cancer38
retinoblastoma21
skin tumor31
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult44
embryoid body100
blastocyst130
neonate32
fetus59
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.8
adrenal gland15
appendix20.4
bone marrow11
cerebral cortex10
colon17.6
duodenum9.3
esophagus15.7
gallbladder17.5
heart muscle11.1
kidney12
liver7.8
lung10.3
lymph node25.1
ovary18.1
pancreas8.7
placenta13.7
prostate14.3
salivary gland10.1
skin11.4
small intestine10.7
spleen14.6
stomach15.8
testis43.9
thyroid gland23.6
urinary bladder18.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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