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> Protein (NX_Q64LD2)
Protein (NX_Q64LD2)
Protein
Gene SymbolWDR25 to neXtProt (NX_Q64LD2)
DescriptionWD repeat-containing protein 25
Chromosome14
Location14q32.2 (100842755 ~ 100996640) to Ensembl
Sequene Features : Isoforms 2, Variants 69, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 69 0
2014-09-19protein level
2 53 0
2014-05-27transcript level
2 53 0
2014-02-25transcript level
2 53 0
2013-12-09transcript level
2 37 0
2013-11-01transcript level
2 36 0
2013-09-12transcript level
2 36 0
2013-08-17transcript level
2 36 0
2013-07-15transcript level
2 31 0
2013-06-11transcript level
2 31 0
2013-02-12protein level
2 18 2
2012-12-20protein level
2 17 2
2012-10-30protein level
2 22 2
2012-10-07protein level
2 22 1
2012-08-24protein level
2 21 1
2012-07-28protein level
2 21 1
2012-06-08protein level
2 24 1
2012-05-07protein level
2 23 1
2012-04-10protein level
2 23 1
2012-01-13protein level
2 11 1
2011-12-20protein level
2 11 1
2011-11-11protein level
2 11 1
2011-08-23protein level
2 11 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q64LD2-1
15 10 0 60122.7231
NX_Q64LD2-2
1 10 0 32144.807
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744560,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
2 EBI-744560,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
3 EBI-744560,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
4 EBI-744560,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
5 EBI-744560,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood49
bone13
brain11
cervix41
connective tissue13
embryonic tissue14
eye28
heart33
intestine8
kidney4
lung29
lymph90
lymph node22
mouth30
muscle37
nerve64
ovary19
placenta52
prostate5
salivary gland49
skin14
testis11
thymus12
uterus17
Health State
TissuesTPM*
normal17
cervical tumor57
chondrosarcoma24
gastrointestinal tumor8
head and neck tumor22
leukemia63
lung tumor58
lymphoma55
ovarian tumor26
primitive neuroectodermal tumor of the CNS78
prostate cancer9
skin tumor23
soft tissue/muscle tissue tumor23
Developmental Stage
TissuesTPM*
adult21
embryoid body28
blastocyst16
fetus16
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.7
adrenal gland6.8
appendix4
bone marrow3.4
cerebral cortex5.1
colon6.1
duodenum4.1
esophagus6.1
gallbladder7
heart muscle5
kidney6
liver3.9
lung5.9
lymph node6.8
ovary7.4
pancreas4.4
placenta5.1
prostate7.3
salivary gland5.7
skin3.9
small intestine3.8
spleen5.3
stomach5.5
testis7.7
thyroid gland16.3
urinary bladder7.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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