Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q676U5)
Protein (NX_Q676U5)
Protein
Gene SymbolATG16L1 to neXtProt (NX_Q676U5)
DescriptionAutophagy-related protein 16-1
Chromosome2
Location2q37.1 (234118697 ~ 234204320) to Ensembl
Sequene Features : Isoforms 5, Variants 58, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein homooligomerization
.negative stranded viral RNA replication
.protein transport
.autophagic vacuole assembly
.identical protein binding .pre-autophagosomal structure membrane
.axoneme
.autophagic vacuole
.autophagic vacuole membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 58 4
2014-09-19protein level
5 51 4
2014-05-27protein level
5 50 4
2014-02-25protein level
5 50 4
2013-12-09protein level
5 42 4
2013-11-01protein level
5 41 3
2013-09-12protein level
5 41 4
2013-08-17protein level
5 41 4
2013-07-15protein level
5 25 4
2013-06-11protein level
5 25 4
2013-02-12protein level
5 8 26
2012-12-20protein level
5 7 26
2012-10-30protein level
5 12 26
2012-10-07protein level
5 12 6
2012-08-24protein level
5 11 6
2012-07-28protein level
5 11 6
2012-06-08protein level
5 14 6
2012-05-07protein level
5 13 6
2012-04-10protein level
4 13 6
2012-01-13protein level
4 6 6
2011-12-20protein level
4 6 6
2011-11-11protein level
4 6 4
2011-08-23protein level
4 6 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q676U5-1
0 25 0 68222.4673
NX_Q676U5-2
0 24 0 66254.3939
NX_Q676U5-3
1 19 0 53186.706
NX_Q676U5-4
1 14 0 47656.3372
NX_Q676U5-5
0 17 0 49455.1565
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-535909,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
2 EBI-535909,EBI-1047793 RB1CC1  
  .negative regulation of extrinsic apoptotic signaling pathway
.positive regulation of cell size
.regulation of autophagy
  + 8 more...
.protein kinase binding .ULK1-ATG13-FIP200 complex
.ATG1/UKL1 signaling complex
.pre-autophagosomal structure membrane
  + 3 more...
3 EBI-535909,EBI-7054441 TMEM59  
  .negative regulation of protein glycosylation in Golgi
.negative regulation of establishment of protein localization to plasma membrane
.negative regulation of protein processing
  + 2 more...
.endopeptidase activity .extracellular exosome
.late endosome membrane
.integral component of membrane
  + 8 more...
4 EBI-535909,EBI-2603996 MAP1LC3C  
  .membrane fusion
.nucleophagy
.cellular response to nitrogen starvation
  + 2 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 6 more...
5 EBI-535909,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood40
bone27
bone marrow41
brain75
cervix41
connective tissue60
embryonic tissue79
eye38
heart55
intestine47
kidney42
liver14
lung47
lymph node33
mammary gland92
mouth45
muscle28
nerve128
ovary39
pancreas32
pharynx24
pituitary gland423
placenta31
prostate15
salivary gland148
skin61
spleen18
stomach41
testis71
thymus138
thyroid42
trachea96
uterus47
vascular19
Health State
TissuesTPM*
normal58
breast (mammary gland) tumor96
cervical tumor57
chondrosarcoma48
colorectal tumor53
gastrointestinal tumor50
germ cell tumor68
glioma37
head and neck tumor52
kidney tumor87
leukemia63
liver tumor10
lung tumor68
non-neoplasia41
ovarian tumor52
pancreatic tumor38
primitive neuroectodermal tumor of the CNS15
prostate cancer9
skin tumor87
soft tissue/muscle tissue tumor103
uterine tumor44
Developmental Stage
TissuesTPM*
adult50
embryoid body85
blastocyst113
fetus89
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.4
adrenal gland9.1
appendix13.2
bone marrow27.3
cerebral cortex12.5
colon13.3
duodenum12.4
esophagus11.6
gallbladder11.3
heart muscle8.4
kidney9.3
liver7.7
lung10.3
lymph node17.6
ovary9.4
pancreas6.6
placenta9.9
prostate14.6
salivary gland6.9
skin13.5
small intestine12.7
spleen12.9
stomach13.7
testis19.1
thyroid gland14.2
urinary bladder12.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610767, gene) Autophagy 16-like 1; ATG16L1OMIM
2(#611081, phenotype) Inflammatory bowel disease 10; IBD10OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center