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> Protein (NX_Q68CP9)
Protein (NX_Q68CP9)
Protein
Gene SymbolARID2 to neXtProt (NX_Q68CP9)
DescriptionAT-rich interactive domain-containing protein 2
Chromosome12
Location12q12 (46123448 ~ 46301823) to Ensembl
Sequene Features : Isoforms 2, Variants 222, PTMs 15 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.chromatin modification
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.nucleosome disassembly
.metal ion binding
.DNA binding
.plasma membrane
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 222 15
2014-09-19protein level
2 179 15
2014-05-27protein level
2 179 16
2014-02-25protein level
2 178 16
2013-12-09protein level
2 149 16
2013-11-01protein level
2 143 13
2013-09-12protein level
2 143 12
2013-08-17protein level
2 143 12
2013-07-15protein level
2 92 10
2013-06-11protein level
2 92 10
2013-02-12protein level
2 41 14
2012-12-20protein level
2 40 14
2012-10-30protein level
3 54 15
2012-10-07protein level
3 54 7
2012-08-24protein level
3 54 7
2012-07-28protein level
3 54 7
2012-06-08protein level
3 90 7
2012-05-07protein level
3 53 7
2012-04-10protein level
3 53 7
2012-01-13protein level
3 36 7
2011-12-20protein level
3 36 7
2011-11-11protein level
3 36 6
2011-08-23protein level
3 36 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q68CP9-1
2 67 0 197267.2616
NX_Q68CP9-3
0 67 0 191302.3192
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-637818,EBI-302489 SMARCA4  
  .negative regulation of G1/S transition of mitotic cell cycle
.positive regulation of pri-miRNA transcription from RNA polymerase II promoter
.lens fiber cell development
  + 37 more...
.lysine-acetylated histone binding
.DNA polymerase binding
.androgen receptor binding
  + 11 more...
.nBAF complex
.npBAF complex
.protein complex
  + 10 more...
2 EBI-637818,EBI-358419 SMARCB1  
  .positive regulation of sequence-specific DNA binding transcription factor activity
.positive regulation of transcription from RNA polymerase II promoter
.mitotic cell cycle phase transition
  + 14 more...
.Tat protein binding
.transcription coactivator activity
.p53 binding
.nBAF complex
.npBAF complex
.protein complex
  + 6 more...
3 EBI-637818,EBI-637807 PBRM1  
  .negative regulation of cell proliferation
.heart development
.mitotic nuclear division
  + 4 more...
.chromatin binding
.DNA binding
.kinetochore
.nuclear chromosome
4 EBI-637818,EBI-455078 SMARCE1  
  .negative regulation of transcription, DNA-templated
.ATP-dependent chromatin remodeling
.metabolic process
  + 4 more...
.protein N-terminus binding
.ligand-dependent nuclear receptor binding
.N-acetyltransferase activity
  + 4 more...
.nBAF complex
.npBAF complex
.protein complex
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder66
bone13
bone marrow61
brain22
cervix20
connective tissue20
embryonic tissue56
eye33
heart11
intestine60
kidney23
larynx85
liver19
lung11
lymph node33
mammary gland72
mouth30
muscle28
ovary29
pharynx24
pituitary gland60
placenta35
prostate36
skin9
testis91
thymus25
thyroid85
trachea38
uterus17
vascular19
Health State
TissuesTPM*
normal30
bladder carcinoma56
breast (mammary gland) tumor75
cervical tumor28
chondrosarcoma48
colorectal tumor97
germ cell tumor87
glioma37
head and neck tumor59
leukemia21
liver tumor20
lung tumor9
non-neoplasia10
ovarian tumor39
primitive neuroectodermal tumor of the CNS7
prostate cancer38
skin tumor7
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult40
embryoid body57
blastocyst48
fetus53
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.4
adrenal gland5
appendix7.1
bone marrow12.6
cerebral cortex4.2
colon6.6
duodenum4.9
esophagus16.9
gallbladder11.5
heart muscle5.3
kidney5.8
liver3.1
lung6
lymph node10
ovary9.2
pancreas3.1
placenta7.2
prostate6.1
salivary gland4.4
skin8.3
small intestine5.2
spleen5.3
stomach5.9
testis25.6
thyroid gland13.6
urinary bladder14.2
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*609539, gene) At-rich interaction domain-containing protein 2; ARID2OMIM
2hepatocellular carcinomaCGP


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