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> Protein (NX_Q68CQ4)
Protein (NX_Q68CQ4)
Protein
Gene SymbolDIEXF to neXtProt (NX_Q68CQ4)
DescriptionDigestive organ expansion factor homolog
Chromosome1
Location1q32.2 (210001352 ~ 210030910) to Ensembl
Sequene Features : Isoforms 1, Variants 104, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.multicellular organismal development
.maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
.poly(A) RNA binding
.U3 snoRNA binding
.rRNA binding
.small-subunit processome
.nucleolus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 104 0
2014-09-19protein level
1 86 0
2014-05-27protein level
1 86 0
2014-02-25protein level
1 85 0
2013-12-09protein level
1 71 0
2013-11-01protein level
1 68 0
2013-09-12protein level
1 68 0
2013-08-17protein level
1 68 0
2013-07-15protein level
1 50 0
2013-06-11protein level
1 50 0
2013-02-12protein level
1 28 1
2012-12-20protein level
1 28 1
2012-10-30protein level
1 29 1
2012-10-07protein level
1 29 1
2012-08-24protein level
1 28 1
2012-07-28protein level
1 28 1
2012-06-08protein level
1 21 1
2012-05-07protein level
1 21 1
2012-04-10protein level
1 21 1
2012-01-13protein level
1 13 1
2011-12-20protein level
1 13 1
2011-11-11protein level
1 13 1
2011-08-23protein level
1 13 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q68CQ4-1
40 0 0 87000.539
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-747711,EBI-10178634 MAGEA11  
  .N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
2 EBI-747711,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
3 EBI-747711,EBI-2548751 MIPOL1  
  .N/A .N/A .nucleus
4 EBI-747711,EBI-3941207 RUFY1  
  .regulation of endocytosis
.endocytosis
.protein transporter activity
.lipid binding
.zinc ion binding
.intracellular membrane-bounded organelle
.early endosome membrane
.cytoplasm
.nucleus
5 EBI-747711,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder66
blood24
bone13
brain37
cervix103
connective tissue40
embryonic tissue4
esophagus49
eye38
heart22
intestine34
kidney66
liver48
lung47
lymph node33
mammary gland39
nerve64
pancreas14
parathyroid48
pharynx49
placenta28
prostate21
skin14
spleen93
stomach31
testis34
thyroid21
trachea19
uterus60
vascular135
Health State
TissuesTPM*
normal37
bladder carcinoma56
breast (mammary gland) tumor42
cervical tumor144
chondrosarcoma36
colorectal tumor17
esophageal tumor57
gastrointestinal tumor25
germ cell tumor72
head and neck tumor14
kidney tumor14
leukemia21
liver tumor72
lung tumor29
lymphoma13
non-neoplasia31
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS133
prostate cancer19
retinoblastoma43
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult31
blastocyst16
neonate64
fetus57
infant42
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3
adrenal gland2.9
appendix4.4
bone marrow1.4
cerebral cortex3.9
colon3.7
duodenum2.5
esophagus3.2
gallbladder3
heart muscle1.9
kidney3.1
liver2
lung2.3
lymph node4.8
ovary7
pancreas1.4
placenta2.6
prostate2.7
salivary gland2.1
skin3.9
small intestine2.4
spleen3.7
stomach3.1
testis2.2
thyroid gland4.2
urinary bladder4.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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