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> Protein (NX_Q69YI7)
Protein (NX_Q69YI7)
Protein
Gene SymbolNAIF1 to neXtProt (NX_Q69YI7)
DescriptionNuclear apoptosis-inducing factor 1
Chromosome9
Location9q34.11 (130823512 ~ 130830485) to Ensembl
Sequene Features : Isoforms 2, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of mitochondrial membrane permeability involved in apoptotic process
.negative regulation of cell growth
.N/A .plasma membrane
.mitochondrion
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 44 0
2014-09-19protein level
2 36 0
2014-05-27protein level
2 36 0
2014-02-25protein level
2 35 0
2013-12-09protein level
2 30 0
2013-11-01protein level
2 30 0
2013-09-12protein level
2 30 0
2013-08-17protein level
2 31 0
2013-07-15protein level
2 24 0
2013-06-11protein level
2 24 0
2013-02-12protein level
2 9 0
2012-12-20protein level
2 9 0
2012-10-30protein level
2 9 0
2012-10-07protein level
2 9 0
2012-08-24protein level
2 6 0
2012-07-28protein level
2 6 0
2012-06-08protein level
2 6 0
2012-05-07protein level
2 6 0
2012-04-10protein level
2 6 0
2012-01-13protein level
2 3 0
2011-12-20protein level
2 3 0
2011-11-11protein level
2 3 0
2011-08-23protein level
2 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q69YI7-1
5 5 0 35142.1965
NX_Q69YI7-2
1 5 0 17985.5139
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10249231,EBI-748961 CCNDBP1  
  .regulation of cell cycle
.cell cycle
.N/A .cytoplasm
.nucleoplasm
.nucleus
2 EBI-10249231,EBI-9087806 SOX14  
  .regulation of neuron migration
.negative regulation of transcription, DNA-templated
.entrainment of circadian clock
  + 3 more...
.sequence-specific DNA binding
.chromatin binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nuclear transcription factor complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
blood24
bone13
bone marrow41
brain19
connective tissue13
embryonic tissue9
esophagus99
eye4
heart44
intestine12
kidney28
liver19
lung23
lymph node11
mammary gland19
mouth75
ovary39
pancreas18
placenta14
prostate5
skin28
spleen112
stomach73
testis11
thymus12
tonsil58
uterus21
vascular19
Health State
TissuesTPM*
normal1
breast (mammary gland) tumor10
chondrosarcoma48
colorectal tumor8
esophageal tumor57
gastrointestinal tumor67
germ cell tumor3
glioma9
head and neck tumor29
kidney tumor29
leukemia21
liver tumor31
lung tumor19
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS55
skin tumor15
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult1
blastocyst16
fetus32
infant42
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.8
adrenal gland5.5
appendix5.3
bone marrow4.7
cerebral cortex3.5
colon4.5
duodenum4
esophagus5.3
gallbladder4.2
heart muscle3.9
kidney4.2
liver3
lung5.1
lymph node6.9
ovary5.4
pancreas2.4
placenta4.6
prostate3.7
salivary gland3.5
skin4.4
small intestine5.2
spleen6.1
stomach4.8
testis11
thyroid gland4.7
urinary bladder4.4
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*610673, gene) Chromosome 9 open reading frame 90; C9ORF90OMIM


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