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> Protein (NX_Q6DKK2)
Protein (NX_Q6DKK2)
Protein
Gene SymbolTTC19 to neXtProt (NX_Q6DKK2)
DescriptionTetratricopeptide repeat protein 19, mitochondrial
Chromosome17
Location17p12 (15902694 ~ 15948329) to Ensembl
Sequene Features : Isoforms 1, Variants 23, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mitochondrial respiratory chain complex III assembly
.cytokinesis
.N/A .midbody
.centrosome
.mitochondrial inner membrane
.mitochondrion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 23 1
2014-09-19protein level
1 15 1
2014-05-27protein level
1 15 1
2014-02-25protein level
1 14 1
2013-12-09protein level
1 12 1
2013-11-01protein level
1 11 1
2013-09-12protein level
1 11 1
2013-08-17protein level
1 11 1
2013-07-15protein level
1 10 0
2013-06-11protein level
1 10 0
2013-02-12protein level
1 7 0
2012-12-20protein level
1 7 0
2012-10-30protein level
1 7 0
2012-10-07protein level
1 7 0
2012-08-24protein level
1 7 0
2012-07-28protein level
1 7 0
2012-06-08protein level
1 9 0
2012-05-07protein level
1 9 0
2012-04-10protein level
1 9 0
2012-01-13protein level
1 10 0
2011-12-20protein level
1 10 0
2011-11-11protein level
1 10 0
2011-08-23protein level
1 10 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6DKK2-1
21 0 0 42429.7056
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-948354,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
2 EBI-948354,EBI-8641936 NAB2  
  .regulation of epidermis development
.myelination
.negative regulation of transcription from RNA polymerase III promoter
  + 5 more...
.transcription corepressor activity .nucleus
3 EBI-948354,EBI-8638439 CCDC36  
  .positive regulation of defense response to virus by host .N/A .N/A
4 EBI-948354,EBI-2686809 L3MBTL3  
  .erythrocyte maturation
.granulocyte differentiation
.macrophage differentiation
  + 3 more...
.N/A .nucleus
5 EBI-948354,EBI-301024 EIF4ENIF1  
  .N/A .poly(A) RNA binding
.protein transporter activity
.intracellular membrane-bounded organelle
.nuclear speck
.PML body
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites75
bladder66
blood32
bone97
brain85
connective tissue13
embryonic tissue75
eye90
heart134
intestine60
kidney94
larynx42
liver43
lung47
lymph node89
mammary gland92
mouth15
muscle37
nerve64
ovary59
pancreas56
parathyroid339
pituitary gland121
placenta56
prostate84
skin37
spleen37
stomach20
testis43
thymus37
thyroid85
trachea96
uterus56
vascular77
Health State
TissuesTPM*
normal69
bladder carcinoma56
breast (mammary gland) tumor32
chondrosarcoma36
colorectal tumor71
gastrointestinal tumor50
germ cell tumor37
glioma55
head and neck tumor37
kidney tumor14
liver tumor41
lung tumor29
lymphoma55
non-neoplasia41
ovarian tumor78
pancreatic tumor66
primitive neuroectodermal tumor of the CNS39
prostate cancer57
retinoblastoma193
skin tumor15
soft tissue/muscle tissue tumor55
uterine tumor66
Developmental Stage
TissuesTPM*
adult63
embryoid body85
blastocyst81
fetus77
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue14.7
adrenal gland32.3
appendix16.1
bone marrow17
cerebral cortex35.4
colon34.3
duodenum30.9
esophagus17.5
gallbladder18.4
heart muscle20.3
kidney33
liver16.6
lung22.4
lymph node16.3
ovary16.6
pancreas14.1
placenta17.7
prostate26
salivary gland18.4
skin22.4
small intestine27.2
spleen15.8
stomach21.2
testis10.5
thyroid gland39.6
urinary bladder22.6
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowLow
breastHigh
bronchusMedium
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverMedium
lungLow
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryHigh
pancreasMedium
parathyroid glandHigh
placentaLow
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleLow
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Low
soft tissue 2High
spleenLow
stomach 1Medium
stomach 2High
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613814, gene) Tetratricopeptide repeat domain 19; TTC19OMIM


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