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> Protein (NX_Q6FIF0)
Protein (NX_Q6FIF0)
Protein
Gene SymbolZFAND6 to neXtProt (NX_Q6FIF0)
DescriptionAN1-type zinc finger protein 6
Chromosome15
Location15q25.1 (80351910 ~ 80430735) to Ensembl
Sequene Features : Isoforms 2, Variants 18, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to tumor necrosis factor
.regulation of I-kappaB kinase/NF-kappaB signaling
.negative regulation of apoptotic process
  + 2 more...
.polyubiquitin binding
.zinc ion binding
.DNA binding
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 18 3
2014-09-19protein level
2 15 3
2014-05-27protein level
2 15 3
2014-02-25protein level
2 15 3
2013-12-09protein level
2 11 3
2013-11-01protein level
2 11 1
2013-09-12protein level
2 11 1
2013-08-17protein level
2 11 1
2013-07-15protein level
2 12 0
2013-06-11protein level
2 12 0
2013-02-12protein level
2 1 0
2012-12-20protein level
2 1 0
2012-10-30protein level
2 1 0
2012-10-07protein level
2 1 0
2012-08-24protein level
2 1 0
2012-07-28transcript level
2 1 0
2012-06-08transcript level
2 5 0
2012-05-07transcript level
2 5 0
2012-04-10transcript level
2 5 0
2012-01-13transcript level
2 7 0
2011-12-20transcript level
2 7 0
2011-11-11transcript level
2 7 0
2011-08-23transcript level
2 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6FIF0-1
1 6 1 22540.5924
NX_Q6FIF0-2
1 6 1 21382.0188
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-724630,EBI-523498 TRAF5  
  .positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
.positive regulation of I-kappaB kinase/NF-kappaB signaling
  + 4 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
  + 2 more...
.CD40 receptor complex
.cytoplasmic side of plasma membrane
.cytosol
  + 2 more...
2 EBI-724630,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites50
bladder66
blood24
bone111
bone marrow20
brain15
cervix61
connective tissue13
ear62
embryonic tissue14
esophagus99
eye23
heart22
intestine8
kidney23
liver43
lung23
lymph22
lymph node111
mammary gland59
muscle37
nerve64
ovary29
pancreas32
parathyroid194
pharynx24
placenta3
prostate47
salivary gland246
skin61
spleen18
stomach10
testis107
thymus12
thyroid107
uterus94
vascular96
Health State
TissuesTPM*
normal21
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor64
cervical tumor57
chondrosarcoma96
colorectal tumor79
esophageal tumor115
gastrointestinal tumor8
germ cell tumor64
glioma27
head and neck tumor29
kidney tumor14
leukemia10
liver tumor41
lung tumor48
lymphoma55
non-neoplasia20
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS39
prostate cancer67
retinoblastoma43
skin tumor63
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult78
embryoid body157
blastocyst16
fetus14
infant212
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue51.2
adrenal gland65.3
appendix48
bone marrow54.8
cerebral cortex27.6
colon54.8
duodenum46.4
esophagus52.1
gallbladder51.7
heart muscle65.5
kidney54.6
liver54
lung51
lymph node68.4
ovary37.1
pancreas19
placenta45.7
prostate51.6
salivary gland37.2
skin34.6
small intestine47.1
spleen52.2
stomach50.9
testis111.8
thyroid gland98.9
urinary bladder62.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610183, gene) Zinc finger an1 domain-containing protein 6; ZFAND6OMIM


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