|
| Protein |
|
| Gene Symbol | ISM2 to neXtProt (NX_Q6H9L7) |
| Description | Isthmin-2 |
| Chromosome | 14 |
| Location | 14q24.3 (77940740 ~ 77965210) to Ensembl |
|
|
Sequene Features : Isoforms 5, Variants 98, PTMs 10 to neXtProt Sequence Features
|
|
Gene
Ontologies |
| GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
.N/A |
.N/A |
.extracellular region |
|
|
| |
|
| Proteomic Evidences |
|
| |
|
| Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
|
| 2015-01-01 | | protein level | | | | | | | 5 |
| 98 |
| 10 |
|
| 2014-09-19 | | protein level | | | | | | | 5 |
| 77 |
| 10 |
|
| 2014-05-27 | | protein level | | | | | | | 5 |
| 75 |
| 10 |
|
| 2014-02-25 | | protein level | | | | | | | 5 |
| 74 |
| 10 |
|
| 2013-12-09 | | protein level | | | | | | | 5 |
| 59 |
| 10 |
|
| 2013-11-01 | | protein level | | | | | | | 5 |
| 55 |
| 10 |
|
| 2013-09-12 | | protein level | | | | | | | 5 |
| 55 |
| 10 |
|
| 2013-08-17 | | protein level | | | | | | | 5 |
| 55 |
| 10 |
|
| 2013-07-15 | | transcript level | | | | | | | 5 |
| 42 |
| 6 |
|
| 2013-06-11 | | transcript level | | | | | | | 5 |
| 42 |
| 6 |
|
| 2013-02-12 | | transcript level | | | | | | | 5 |
| 25 |
| 18 |
|
| 2012-12-20 | | transcript level | | | | | | | 5 |
| 24 |
| 18 |
|
| 2012-10-30 | | transcript level | | | | | | | 5 |
| 26 |
| 18 |
|
| 2012-10-07 | | transcript level | | | | | | | 5 |
| 26 |
| 6 |
|
| 2012-08-24 | | transcript level | | | | | | | 5 |
| 23 |
| 6 |
|
| 2012-07-28 | | transcript level | | | | | | | 5 |
| 23 |
| 6 |
|
| 2012-06-08 | | transcript level | | | | | | | 5 |
| 25 |
| 6 |
|
| 2012-05-07 | | transcript level | | | | | | | 5 |
| 25 |
| 6 |
|
| 2012-04-10 | | transcript level | | | | | | | 5 |
| 25 |
| 6 |
|
| 2012-01-13 | | transcript level | | | | | | | 5 |
| 8 |
| 6 |
|
| 2011-12-20 | | transcript level | | | | | | | 5 |
| 8 |
| 6 |
|
| 2011-11-11 | | transcript level | | | | | | | 5 |
| 8 |
| 6 |
|
| 2011-08-23 | | transcript level | | | | | | | 5 |
| 8 |
| 6 |
|
|
| |
|
| Protein Isoforms |
|
| |
| |
|
| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
|
|
| |
|
| EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
|
| |
|
| Body Sites | |
| Tissues | TPM* | |
|
| kidney | 4 | |
| ovary | 9 | |
| placenta | 1017 | |
| prostate | 15 | |
| skin | 4 | |
| testis | 22 | |
| uterus | 30 | |
| vascular | 38 | |
|
| Health State | |
| Tissues | TPM* | |
|
| normal | 90 | |
| germ cell tumor | 11 | |
| ovarian tumor | 13 | |
|
| Developmental Stage | |
| Tissues | TPM* | |
|
| adult | 154 | |
| fetus | 10 | |
|
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
| |
|
| Expression level of Protein (ref. Human Protein Atlas) |
|
| |
|
| RNA-Seq. | |
| Tissues | FPKM | |
|
| placenta | 159.6 | |
| testis | 1.8 | |
|
| Tissues | |
| Tissues | Expression level |
|
| placenta | Medium | |
|
| Cancer | |
| Tumor | Number of patients and Staining levels | |
| breast cancer | |
| carcinoid | |
| cervical cancer | |
| colorectal cancer | |
| endometrial cancer | |
| glioma | |
| head and neck cancer | |
| liver cancer | |
| lung cancer | |
| lymphoma | |
| melanoma | |
| ovarian cancer | |
| pancreatic cancer | |
| prostate cancer | |
| renal cancer | |
| skin cancer | |
| stomach cancer | |
| testis cancer | |
| thyroid cancer | |
| urothelial cancer | |
|
| RNA-seq colour codes |
|
|
Highly expressed RNAs (FPKM >50) | |
|
Moderately expressed RNAs (50> FPKM >10) | |
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Lower expressed RNAs (10> FPKM >1) | |
|
The lowest expressed RNAs (FPKM value of 0 or 1) |
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| Expression level colour codes |
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|
Highly expressed protein | |
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Moderately expressed protein | |
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Lower expressed protein |
|
| Staining level colour codes |
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|
Highly expressed protein | |
|
Moderately expressed protein | |
|
Lower expressed protein | |
|
Not Detected |
|
|
| |
|
| Disease |
|
| |
|
| No. | Disease Description | Ref. |
|
| 1 | (*612684, gene) Isthmin 2, zebrafish, homolog of; ISM2 | OMIM |
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> Protein (NX_Q6H9L7)