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> Protein (NX_Q6IA86)
Protein (NX_Q6IA86)
Protein
Gene SymbolELP2 to neXtProt (NX_Q6IA86)
DescriptionElongator complex protein 2
Chromosome18
Location18q12.2 (33709407 ~ 33757909) to Ensembl
Sequene Features : Isoforms 7, Variants 106, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of JAK-STAT cascade
.transcription elongation from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.chromatin organization
.N/A .Elongator holoenzyme complex
.transcription elongation factor complex
.cytoplasm
.histone acetyltransferase complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
7 106 4
2014-09-19protein level
7 94 4
2014-05-27protein level
7 94 4
2014-02-25protein level
7 92 4
2013-12-09protein level
7 70 4
2013-11-01protein level
7 69 2
2013-09-12protein level
7 69 2
2013-08-17protein level
7 69 2
2013-07-15protein level
7 55 0
2013-06-11protein level
7 55 0
2013-02-12protein level
7 38 0
2012-12-20protein level
5 41 0
2012-10-30protein level
5 45 0
2012-10-07protein level
5 45 0
2012-08-24protein level
5 43 0
2012-07-28protein level
5 42 0
2012-06-08protein level
5 43 0
2012-05-07protein level
5 43 0
2012-04-10protein level
4 38 0
2012-01-13protein level
4 30 0
2011-12-20protein level
4 30 0
2011-11-11protein level
4 30 0
2011-08-23protein level
4 30 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6IA86-1
0 35 0 92440.6003
NX_Q6IA86-2
0 34 0 84833.9601
NX_Q6IA86-3
0 35 0 89657.2593
NX_Q6IA86-4
2 29 0 78526.2514
NX_Q6IA86-5
0 37 0 92316.7419
NX_Q6IA86-6
1 38 0 99923.3821
NX_Q6IA86-7
0 31 0 84633.8623
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue310
adrenal gland151
ascites125
bladder66
blood49
bone marrow123
brain95
connective tissue167
embryonic tissue98
esophagus99
eye100
heart100
intestine60
kidney99
liver43
lung68
lymph45
lymph node66
mammary gland198
mouth60
muscle18
ovary39
pancreas37
pharynx98
placenta109
prostate79
salivary gland197
skin113
spleen187
stomach41
testis112
thymus263
thyroid193
tonsil58
trachea154
uterus155
vascular77
Health State
TissuesTPM*
normal88
adrenal tumor79
breast (mammary gland) tumor268
chondrosarcoma48
colorectal tumor26
esophageal tumor115
gastrointestinal tumor59
germ cell tumor170
glioma46
head and neck tumor119
kidney tumor72
leukemia10
liver tumor41
lung tumor116
lymphoma96
non-neoplasia41
ovarian tumor52
pancreatic tumor47
primitive neuroectodermal tumor of the CNS86
prostate cancer28
retinoblastoma193
skin tumor119
soft tissue/muscle tissue tumor215
uterine tumor110
Developmental Stage
TissuesTPM*
adult74
embryoid body100
blastocyst48
neonate96
fetus109
infant85
juvenile161
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue27.4
adrenal gland30.5
appendix27.8
bone marrow33
cerebral cortex22.2
colon22.2
duodenum21.2
esophagus22.7
gallbladder29
heart muscle27.2
kidney23.9
liver32.6
lung27.6
lymph node34.1
ovary60.4
pancreas16.4
placenta29
prostate38
salivary gland23.4
skin35.7
small intestine21.9
spleen29.6
stomach23.9
testis34.4
thyroid gland33.6
urinary bladder32.9
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2Medium
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleLow
liverLow
lungMedium
lymph nodeMedium
nasopharynxHigh
oral mucosaMedium
ovaryMedium
pancreasHigh
parathyroid glandLow
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleHigh
skin 1Medium
skin 2Low
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilMedium
urinary bladderHigh
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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