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> Protein (NX_Q6NSJ5)
Protein (NX_Q6NSJ5)
Protein
Gene SymbolLRRC8E to neXtProt (NX_Q6NSJ5)
DescriptionVolume-regulated anion channel subunit LRRC8E
Chromosome19
Location19p13.2 (7953390 ~ 7966901) to Ensembl
Sequene Features : Isoforms 1, Variants 92, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ion transport .N/A .integral component of membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 92 2
2014-09-19protein level
1 75 2
2014-05-27protein level
1 75 2
2014-02-25protein level
1 74 2
2013-12-09protein level
1 49 2
2013-11-01protein level
1 47 2
2013-09-12protein level
1 47 2
2013-08-17protein level
1 47 2
2013-07-15protein level
1 39 2
2013-06-11protein level
1 39 2
2013-02-12protein level
1 26 2
2012-12-20protein level
1 27 2
2012-10-30protein level
1 30 2
2012-10-07protein level
1 30 2
2012-08-24protein level
1 30 2
2012-07-28protein level
1 30 2
2012-06-08protein level
1 35 2
2012-05-07protein level
1 28 2
2012-04-10protein level
1 28 2
2012-01-13protein level
1 15 2
2011-12-20protein level
1 15 2
2011-11-11protein level
1 15 2
2011-08-23transcript level
1 15 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6NSJ5-1
38 0 2 90189.1693
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
bone27
brain1
cervix20
embryonic tissue4
intestine17
kidney14
larynx127
liver4
lung11
mouth120
ovary19
pancreas18
placenta31
prostate21
skin4
testis2
thyroid21
trachea19
uterus4
Health State
TissuesTPM*
normal6
bladder carcinoma56
cervical tumor28
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor8
germ cell tumor15
head and neck tumor89
kidney tumor43
liver tumor10
lung tumor19
pancreatic tumor38
uterine tumor11
Developmental Stage
TissuesTPM*
adult12
embryoid body14
neonate32
fetus1
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland3.4
esophagus4.1
gallbladder2.4
kidney1.3
liver2.7
lung3.3
pancreas2.8
placenta1.4
prostate3.1
salivary gland5.1
skin5.3
stomach3
thyroid gland1.5
urinary bladder2.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612891, gene) Leucine-rich repeat-containing protein 8e; LRRC8EOMIM


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