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> Protein (NX_Q6NX49)
Protein (NX_Q6NX49)
Protein
Gene SymbolZNF544 to neXtProt (NX_Q6NX49)
DescriptionZinc finger protein 544
Chromosome19
Location19q13.43 (58739960 ~ 58788815) to Ensembl
Sequene Features : Isoforms 1, Variants 100, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 100 0
2014-09-19transcript level
1 84 0
2014-05-27transcript level
1 84 0
2014-02-25transcript level
1 83 0
2013-12-09transcript level
1 59 0
2013-11-01transcript level
1 57 0
2013-09-12transcript level
1 57 0
2013-08-17transcript level
1 57 0
2013-07-15transcript level
1 38 0
2013-06-11transcript level
1 38 0
2013-02-12transcript level
1 26 0
2012-12-20transcript level
1 25 0
2012-10-30transcript level
1 30 0
2012-10-07transcript level
1 30 0
2012-08-24transcript level
1 30 0
2012-07-28transcript level
1 30 0
2012-06-08transcript level
1 36 0
2012-05-07transcript level
1 33 0
2012-04-10transcript level
1 33 0
2012-01-13transcript level
1 11 0
2011-12-20transcript level
1 11 0
2011-11-11transcript level
1 11 0
2011-08-23transcript level
1 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6NX49-1
37 0 3 81688.9718
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2841978,EBI-374781 GLRX3  
  .cell redox homeostasis
.negative regulation of cardiac muscle hypertrophy
.regulation of the force of heart contraction
.iron-sulfur cluster binding
.metal ion binding
.poly(A) RNA binding
  + 2 more...
.extracellular exosome
.Z disc
.cell cortex
2 EBI-2841978,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
3 EBI-2841978,EBI-744794 TSGA10  
  .cell projection assembly
.spermatogenesis
.N/A .neuron projection
.nuclear membrane
.motile cilium
.cytoplasm
4 EBI-2841978,EBI-928842 NDEL1  
  .neuron projection extension
.neurofilament cytoskeleton organization
.centrosome localization
  + 20 more...
.oligopeptidase activity
.microtubule binding
.neurofilament cytoskeleton
.axon hillock
.cell leading edge
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
blood32
bone13
brain47
cervix20
connective tissue26
embryonic tissue37
esophagus99
eye38
heart44
intestine4
kidney18
larynx42
liver38
lung50
lymph22
lymph node33
mammary gland26
mouth166
muscle37
nerve64
ovary19
pancreas14
pharynx49
placenta74
prostate68
skin42
spleen74
testis105
thymus87
thyroid21
trachea96
uterus34
vascular58
Health State
TissuesTPM*
normal39
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma12
esophageal tumor115
gastrointestinal tumor8
germ cell tumor68
glioma27
head and neck tumor89
kidney tumor29
leukemia10
liver tumor41
lung tumor48
lymphoma55
non-neoplasia51
ovarian tumor13
pancreatic tumor28
primitive neuroectodermal tumor of the CNS23
prostate cancer57
retinoblastoma43
skin tumor63
soft tissue/muscle tissue tumor15
uterine tumor66
Developmental Stage
TissuesTPM*
adult39
embryoid body28
blastocyst48
neonate32
fetus34
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.6
adrenal gland12.7
appendix9.9
bone marrow7
cerebral cortex12.1
colon9.8
duodenum6.1
esophagus11.1
gallbladder11.7
heart muscle15.5
kidney10.9
liver5.7
lung10.8
lymph node14.8
ovary15.3
pancreas6.4
placenta12.3
prostate12.4
salivary gland7.3
skin11.4
small intestine9
spleen11.4
stomach9.5
testis20.5
thyroid gland20.4
urinary bladder17.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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