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> Protein (NX_Q6P9G9)
Protein (NX_Q6P9G9)
Protein
Gene SymbolZNF449 to neXtProt (NX_Q6P9G9)
DescriptionZinc finger protein 449
ChromosomeX
LocationXq26.3 (134478721 ~ 134497077) to Ensembl
Sequene Features : Isoforms 3, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
3 65 0
2014-09-19transcript level
3 52 0
2014-05-27transcript level
3 52 0
2014-02-25transcript level
3 52 0
2013-12-09transcript level
3 47 0
2013-11-01transcript level
3 43 0
2013-09-12transcript level
3 43 0
2013-08-17transcript level
3 43 0
2013-07-15transcript level
3 23 0
2013-06-11transcript level
3 23 0
2013-02-12transcript level
3 12 0
2012-12-20transcript level
3 12 0
2012-10-30transcript level
3 14 0
2012-10-07transcript level
3 14 0
2012-08-24transcript level
3 13 0
2012-07-28transcript level
3 13 0
2012-06-08transcript level
3 10 0
2012-05-07transcript level
3 10 0
2012-04-10transcript level
3 10 0
2012-01-13transcript level
3 4 0
2011-12-20transcript level
3 4 0
2011-11-11transcript level
3 4 0
2011-08-23transcript level
3 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6P9G9-1
16 5 3 59893.6019
NX_Q6P9G9-2
4 5 0 19219.7077
NX_Q6P9G9-3
1 5 0 15101.4322
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10215956,EBI-745846 SCAND1  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.identical protein binding
.transcription coactivator activity
.sequence-specific DNA binding transcription factor activity
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bone27
brain14
connective tissue13
embryonic tissue18
eye4
intestine17
kidney9
liver4
lung2
lymph node11
mouth45
muscle9
placenta35
prostate5
spleen18
stomach10
testis22
trachea19
uterus25
vascular19
Health State
TissuesTPM*
normal16
chondrosarcoma12
colorectal tumor35
gastrointestinal tumor8
germ cell tumor11
head and neck tumor7
non-neoplasia10
uterine tumor22
Developmental Stage
TissuesTPM*
adult11
embryoid body28
blastocyst16
fetus10
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.2
adrenal gland7.5
appendix6.3
bone marrow1.2
cerebral cortex4.6
colon2.9
duodenum3
esophagus4.5
gallbladder6.4
heart muscle4.3
kidney2.7
liver1.5
lung6
lymph node4.1
ovary4.2
pancreas3.1
placenta4.9
prostate6
salivary gland2.4
skin3.3
small intestine2.6
spleen5.2
stomach4
testis3.6
thyroid gland6.5
urinary bladder4.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300627, gene) Zinc finger protein 449; ZNF449OMIM


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