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> Protein (NX_Q6PKG0)
Protein (NX_Q6PKG0)
Protein
Gene SymbolLARP1 to neXtProt (NX_Q6PKG0)
DescriptionLa-related protein 1
Chromosome5
Location5q33.2 (154092462 ~ 154197167) to Ensembl
Sequene Features : Isoforms 2, Variants 114, PTMs 47 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of translation
.TOR signaling
.positive regulation of macroautophagy
  + 2 more...
.mRNA 5'-UTR binding
.poly(A) RNA binding
.translation initiation factor binding
  + 4 more...
.membrane
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 114 47
2014-09-19protein level
2 83 47
2014-05-27protein level
2 82 47
2014-02-25protein level
2 83 47
2013-12-09protein level
2 69 47
2013-11-01protein level
2 68 41
2013-09-12protein level
2 68 42
2013-08-17protein level
2 68 42
2013-07-15protein level
2 40 40
2013-06-11protein level
2 40 40
2013-02-12protein level
2 17 84
2012-12-20protein level
2 18 84
2012-10-30protein level
2 22 84
2012-10-07protein level
2 22 44
2012-08-24protein level
2 21 44
2012-07-28protein level
2 21 44
2012-06-08protein level
2 2 44
2012-05-07protein level
2 2 44
2012-04-10protein level
2 2 44
2012-01-13protein level
2 2 44
2011-12-20protein level
2 3 44
2011-11-11protein level
2 3 41
2011-08-23protein level
2 3 41
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6PKG0-1
9 42 3 123433.8234
NX_Q6PKG0-3
3 42 3 116392.5021
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1052114,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites251
bladder66
blood106
bone125
bone marrow41
brain111
cervix164
connective tissue127
ear124
embryonic tissue216
eye181
heart134
intestine176
kidney90
larynx85
liver116
lung164
lymph293
lymph node479
mammary gland416
mouth60
muscle131
nerve128
ovary157
pancreas126
parathyroid145
pharynx49
pituitary gland181
placenta81
prostate84
salivary gland148
skin246
spleen37
stomach83
testis232
thymus62
thyroid236
tonsil58
uterus116
vascular77
Health State
TissuesTPM*
normal120
bladder carcinoma56
breast (mammary gland) tumor612
cervical tumor231
chondrosarcoma217
colorectal tumor239
gastrointestinal tumor194
germ cell tumor167
glioma251
head and neck tumor134
kidney tumor159
leukemia190
liver tumor145
lung tumor175
lymphoma263
non-neoplasia103
ovarian tumor144
pancreatic tumor190
primitive neuroectodermal tumor of the CNS125
prostate cancer96
retinoblastoma107
skin tumor239
soft tissue/muscle tissue tumor127
uterine tumor122
Developmental Stage
TissuesTPM*
adult158
embryoid body257
blastocyst211
fetus109
infant42
juvenile161
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue38.7
adrenal gland39.9
appendix43.2
bone marrow22.3
cerebral cortex45.8
colon34.4
duodenum32.7
esophagus39.8
gallbladder32.3
heart muscle42.2
kidney41.1
liver18.1
lung28.3
lymph node42.3
ovary47.9
pancreas50.1
placenta39.6
prostate26.7
salivary gland44.3
skin32.6
small intestine30.7
spleen39.3
stomach39.4
testis48
thyroid gland63.9
urinary bladder32.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612059, gene) La ribonucleoprotein domain family, member 1; LARP1OMIM


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