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> Protein (NX_Q6PKX4)
Protein (NX_Q6PKX4)
Protein
Gene SymbolDOK6 to neXtProt (NX_Q6PKX4)
DescriptionDocking protein 6
Chromosome18
Location18q22.2 (67068291 ~ 67516323) to Ensembl
Sequene Features : Isoforms 1, Variants 62, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 62 0
2014-09-19protein level
1 43 0
2014-05-27protein level
1 43 0
2014-02-25protein level
1 42 0
2013-12-09protein level
1 39 0
2013-11-01protein level
1 35 0
2013-09-12protein level
1 35 0
2013-08-17protein level
1 35 0
2013-07-15protein level
1 19 0
2013-06-11protein level
1 19 0
2013-02-12protein level
1 13 0
2012-12-20protein level
1 13 0
2012-10-30protein level
1 15 0
2012-10-07protein level
1 15 0
2012-08-24protein level
1 13 0
2012-07-28protein level
1 13 0
2012-06-08protein level
1 14 0
2012-05-07protein level
1 8 0
2012-04-10protein level
1 8 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6PKX4-1
17 0 1 38292.9894
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2880244,EBI-297353 EGFR  
  .cellular response to dexamethasone stimulus
.cellular response to estradiol stimulus
.cellular response to epidermal growth factor stimulus
  + 73 more...
.actin filament binding
.protein heterodimerization activity
.identical protein binding
  + 12 more...
.multivesicular body, internal vesicle lumen
.Shc-EGFR complex
.perinuclear region of cytoplasm
  + 19 more...
2 EBI-2880244,EBI-946029 C1orf94  
  .N/A .N/A .N/A
3 EBI-2880244,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain25
connective tissue20
ear124
eye28
kidney4
muscle9
ovary9
pancreas4
parathyroid48
placenta28
testis11
Health State
TissuesTPM*
normal17
chondrosarcoma12
germ cell tumor15
glioma18
kidney tumor14
ovarian tumor13
retinoblastoma43
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult15
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.7
adrenal gland1.2
cerebral cortex14.3
colon1.1
duodenum1.1
esophagus2.5
gallbladder11.9
heart muscle17.4
kidney7.3
liver2
lung4.6
lymph node1.4
ovary3.8
placenta10
prostate1.5
skin1.2
small intestine1.1
spleen1.4
testis6
thyroid gland7.4
urinary bladder7.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611402, gene) Docking protein 6; DOK6OMIM


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