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> Protein (NX_Q6QEF8)
Protein (NX_Q6QEF8)
Protein
Gene SymbolCORO6 to neXtProt (NX_Q6QEF8)
DescriptionCoronin-6
Chromosome17
Location17q11.2 (27941774 ~ 27949925) to Ensembl
Sequene Features : Isoforms 5, Variants 48, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.actin cytoskeleton organization .actin filament binding .actin cytoskeleton
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 48 0
2014-09-19protein level
5 31 0
2014-05-27protein level
5 31 0
2014-02-25protein level
5 30 0
2013-12-09protein level
5 20 0
2013-11-01protein level
5 19 0
2013-09-12protein level
5 19 0
2013-08-17protein level
5 19 0
2013-07-15protein level
5 13 0
2013-06-11protein level
5 13 0
2013-02-12protein level
5 3 5
2012-12-20protein level
5 3 5
2012-10-30protein level
5 4 5
2012-10-07protein level
5 4 1
2012-08-24protein level
5 4 1
2012-07-28protein level
5 4 1
2012-06-08protein level
5 1 1
2012-05-07protein level
5 1 1
2012-04-10protein level
5 1 1
2012-01-13protein level
5 1 1
2011-12-20protein level
5 3 1
2011-11-11protein level
5 3 1
2011-08-23protein level
5 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6QEF8-1
4 13 1 52728.6565
NX_Q6QEF8-2
0 9 1 31768.7848
NX_Q6QEF8-3
0 9 1 31640.7266
NX_Q6QEF8-4
2 5 1 26866.2756
NX_Q6QEF8-5
3 13 1 52954.6697
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10254194,EBI-465781 BLOC1S6  
  .membrane fusion
.membrane organization
.positive regulation of pigment cell differentiation
  + 12 more...
.actin filament binding
.protein homodimerization activity
.identical protein binding
.syntaxin binding
.BLOC-1 complex
.transport vesicle
.extrinsic component of membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood8
bone13
brain21
connective tissue6
embryonic tissue9
eye4
heart22
kidney4
larynx127
liver4
lung14
lymph67
mammary gland33
mouth45
muscle94
nerve193
placenta88
skin9
testis6
thyroid21
uterus8
Health State
TissuesTPM*
normal24
breast (mammary gland) tumor53
head and neck tumor22
leukemia10
liver tumor10
lymphoma41
non-neoplasia31
primitive neuroectodermal tumor of the CNS31
skin tumor7
Developmental Stage
TissuesTPM*
adult30
blastocyst32
fetus16
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.8
adrenal gland3.1
appendix2.2
cerebral cortex9.5
colon3.9
duodenum2.7
esophagus16.8
gallbladder6.7
heart muscle62.9
kidney1
lung4.9
lymph node1.9
ovary1.3
placenta47.1
prostate15.5
salivary gland2.1
skin5.9
small intestine3.1
spleen1.8
testis2
thyroid gland38.6
urinary bladder6.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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