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> Protein (NX_Q6QNY0)
Protein (NX_Q6QNY0)
Protein
Gene SymbolBLOC1S3 to neXtProt (NX_Q6QNY0)
DescriptionBiogenesis of lysosome-related organelles complex 1 subunit 3
Chromosome19
Location19q13.32 (45682003 ~ 45685059) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane organization
.platelet dense granule organization
.anterograde synaptic vesicle transport
  + 12 more...
.N/A .BLOC-1 complex
.transport vesicle
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 3
2014-09-19protein level
1 7 3
2014-05-27protein level
1 7 3
2014-02-25protein level
1 7 3
2013-12-09protein level
1 2 3
2013-11-01protein level
1 2 3
2013-09-12protein level
1 2 3
2013-08-17protein level
1 2 3
2013-07-15protein level
1 2 3
2013-06-11protein level
1 2 3
2013-02-12protein level
1 1 6
2012-12-20protein level
1 1 6
2012-10-30protein level
1 1 6
2012-10-07protein level
1 1 6
2012-08-24protein level
1 0 6
2012-07-28protein level
1 0 6
2012-06-08protein level
1 1 6
2012-05-07protein level
1 3 6
2012-04-10protein level
1 3 6
2012-01-13protein level
1 1 6
2011-12-20protein level
1 1 6
2011-11-11protein level
1 1 6
2011-08-23protein level
1 1 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6QNY0-1
11 0 0 21242.8306
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-465930,EBI-465872 BLOC1S2  
  .mitochondrial outer membrane permeabilization
.platelet dense granule organization
.anterograde synaptic vesicle transport
  + 8 more...
.gamma-tubulin binding
.protein C-terminus binding
.recycling endosome
.BLOC-1 complex
.centrosome
  + 3 more...
2 EBI-465930,EBI-465804 DTNBP1  
  .membrane organization
.regulation of dopamine receptor signaling pathway
.platelet dense granule organization
  + 11 more...
.N/A .postsynaptic membrane
.dendritic spine
.neuron projection
  + 14 more...
3 EBI-465930,EBI-465781 BLOC1S6  
  .membrane fusion
.membrane organization
.positive regulation of pigment cell differentiation
  + 12 more...
.actin filament binding
.protein homodimerization activity
.identical protein binding
.syntaxin binding
.BLOC-1 complex
.transport vesicle
.extrinsic component of membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood8
bone13
brain6
eye4
intestine25
kidney9
liver9
lung5
lymph22
mammary gland26
mouth15
muscle9
ovary29
pancreas4
placenta3
prostate5
salivary gland49
skin9
stomach10
testis4
thymus12
thyroid21
uterus4
Health State
TissuesTPM*
normal6
breast (mammary gland) tumor21
colorectal tumor17
gastrointestinal tumor8
germ cell tumor26
glioma27
head and neck tumor22
leukemia21
lung tumor9
lymphoma13
ovarian tumor39
primitive neuroectodermal tumor of the CNS15
Developmental Stage
TissuesTPM*
adult6
fetus10
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.1
adrenal gland3.1
appendix5.4
bone marrow6.3
cerebral cortex3.6
colon4.2
duodenum4.2
esophagus2.9
gallbladder3.1
heart muscle2.6
kidney3.4
liver2
lung5
lymph node6.4
ovary4.7
pancreas1.8
placenta3.7
prostate3.7
salivary gland3.4
skin7.4
small intestine3.6
spleen7.1
stomach5.9
testis5.2
thyroid gland3.6
urinary bladder3.9
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*609762, gene) Biogenesis of lysosome-related organelles complex 1, subunit 3; BLOC1S3OMIM
2(#614077, phenotype) Hermansky-pudlak syndrome 8; HPS8OMIM


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