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> Protein (NX_Q6RFH5)
Protein (NX_Q6RFH5)
Protein
Gene SymbolWDR74 to neXtProt (NX_Q6RFH5)
DescriptionWD repeat-containing protein 74
Chromosome11
Location11q12.3 (62599814 ~ 62609281) to Ensembl
Sequene Features : Isoforms 2, Variants 32, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA metabolic process
.blastocyst formation
.N/A .nucleolus
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 32 13
2014-09-19protein level
2 23 13
2014-05-27protein level
2 23 13
2014-02-25protein level
2 22 12
2013-12-09protein level
2 12 12
2013-11-01protein level
2 12 12
2013-09-12protein level
2 12 12
2013-08-17protein level
2 12 12
2013-07-15protein level
2 6 5
2013-06-11protein level
2 6 5
2013-02-12protein level
2 2 8
2012-12-20protein level
2 2 8
2012-10-30protein level
2 2 8
2012-10-07protein level
2 2 4
2012-08-24protein level
2 1 4
2012-07-28protein level
2 1 4
2012-06-08protein level
2 4 4
2012-05-07protein level
2 4 4
2012-04-10protein level
2 4 4
2012-01-13protein level
2 5 4
2011-12-20protein level
2 5 4
2011-11-11protein level
2 5 3
2011-08-23protein level
2 5 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6RFH5-1
2 16 0 42414.5403
NX_Q6RFH5-2
1 16 0 40182.4105
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-722366,EBI-947779 RCHY1  
  .error-free translesion synthesis
.protein autoubiquitination
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
  + 5 more...
.protein homodimerization activity
.ligase activity
.zinc ion binding
  + 2 more...
.nuclear speck
.cytoplasm
.nucleoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
ascites50
bladder33
blood16
bone55
bone marrow20
brain30
cervix123
connective tissue46
embryonic tissue56
eye43
heart67
intestine64
kidney33
liver77
lung68
lymph67
lymph node66
mammary gland46
muscle28
ovary68
pancreas37
parathyroid97
placenta45
prostate58
skin66
spleen56
stomach20
testis20
thymus12
tonsil58
uterus38
vascular19
Health State
TissuesTPM*
normal35
bladder carcinoma170
breast (mammary gland) tumor64
cervical tumor86
chondrosarcoma48
colorectal tumor62
gastrointestinal tumor59
germ cell tumor45
glioma74
kidney tumor14
leukemia52
liver tumor41
lung tumor145
lymphoma96
non-neoplasia31
ovarian tumor78
pancreatic tumor38
primitive neuroectodermal tumor of the CNS78
prostate cancer67
retinoblastoma64
skin tumor111
soft tissue/muscle tissue tumor63
uterine tumor33
Developmental Stage
TissuesTPM*
adult44
embryoid body57
blastocyst97
fetus23
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.5
adrenal gland19.7
appendix23.9
bone marrow53.2
cerebral cortex18.5
colon18.3
duodenum20
esophagus17.3
gallbladder13.9
heart muscle12.5
kidney19.6
liver14.1
lung18.2
lymph node29
ovary29.2
pancreas14.8
placenta16.5
prostate20
salivary gland16.5
skin34.7
small intestine16.3
spleen27.1
stomach18.8
testis26.8
thyroid gland19.2
urinary bladder15.4
Tissues
TissuesExpression level
breastLow
heart muscleLow
skeletal muscleMedium
skin 2Low
smooth muscleMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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