|
| Protein |
|
| Gene Symbol | RUFY4 to neXtProt (NX_Q6ZNE9) |
| Description | RUN and FYVE domain-containing protein 4 |
| Chromosome | 2 |
| Location | 2q35 (218899683 ~ 218955304) to Ensembl |
|
|
Sequene Features : Isoforms 2, Variants 85, PTMs 0 to neXtProt Sequence Features
|
|
Gene
Ontologies |
| GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
.N/A |
.metal ion binding |
.N/A |
|
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| |
|
| Proteomic Evidences |
|
| |
|
| Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
|
| 2015-01-01 | | transcript level | | | | | | | 2 |
| 85 |
| 0 |
|
| 2014-09-19 | | transcript level | | | | | | | 2 |
| 65 |
| 0 |
|
| 2014-05-27 | | transcript level | | | | | | | 2 |
| 64 |
| 0 |
|
| 2014-02-25 | | transcript level | | | | | | | 2 |
| 63 |
| 0 |
|
| 2013-12-09 | | transcript level | | | | | | | 2 |
| 38 |
| 0 |
|
| 2013-11-01 | | transcript level | | | | | | | 2 |
| 37 |
| 0 |
|
| 2013-09-12 | | transcript level | | | | | | | 2 |
| 37 |
| 0 |
|
| 2013-08-17 | | transcript level | | | | | | | 2 |
| 37 |
| 0 |
|
| 2013-07-15 | | transcript level | | | | | | | 2 |
| 25 |
| 0 |
|
| 2013-06-11 | | transcript level | | | | | | | 2 |
| 25 |
| 0 |
|
| 2013-02-12 | | transcript level | | | | | | | 2 |
| 16 |
| 0 |
|
| 2012-12-20 | | transcript level | | | | | | | 2 |
| 20 |
| 0 |
|
| 2012-10-30 | | transcript level | | | | | | | 2 |
| 25 |
| 0 |
|
| 2012-10-07 | | transcript level | | | | | | | 2 |
| 25 |
| 0 |
|
| 2012-08-24 | | transcript level | | | | | | | 2 |
| 25 |
| 0 |
|
| 2012-07-28 | | transcript level | | | | | | | 2 |
| 25 |
| 0 |
|
| 2012-06-08 | | transcript level | | | | | | | 2 |
| 25 |
| 0 |
|
| 2012-05-07 | | transcript level | | | | | | | 2 |
| 23 |
| 0 |
|
| 2012-04-10 | | transcript level | | | | | | | 2 |
| 23 |
| 0 |
|
| 2012-01-13 | | transcript level | | | | | | | 2 |
| 15 |
| 0 |
|
| 2011-12-20 | | transcript level | | | | | | | 2 |
| 15 |
| 0 |
|
| 2011-11-11 | | transcript level | | | | | | | 2 |
| 15 |
| 0 |
|
| 2011-08-23 | | transcript level | | | | | | | 2 |
| 15 |
| 0 |
|
|
| |
|
| Protein Isoforms |
|
| |
| |
|
| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
|
|
| |
|
| Interacting Partners |
|
| |
|
| No. |
Exp. ref. |
Symbol |
|
PE |
Pr |
Ab |
Di |
|
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
| 1 |
EBI-10181525,EBI-715849 |
NDC80 |
|
| | | | |
.attachment of mitotic spindle microtubules to kinetochore
.cell division
.attachment of spindle microtubules to kinetochore
+ 7 more... |
.identical protein binding
.structural constituent of cytoskeleton |
.Ndc80 complex
.membrane
.cytosol
+ 5 more... |
|
| 2 |
EBI-10181525,EBI-739832 |
LNX1 |
|
| | | | |
.protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity |
.cytoplasm |
|
|
| |
|
| EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
|
| |
|
| Body Sites | |
| Tissues | TPM* | |
|
| brain | 3 | |
| eye | 4 | |
| mammary gland | 6 | |
| muscle | 18 | |
| ovary | 19 | |
| prostate | 5 | |
| spleen | 18 | |
| thymus | 87 | |
| uterus | 4 | |
|
| Health State | |
| Tissues | TPM* | |
|
| normal | 2 | |
| breast (mammary gland) tumor | 10 | |
| ovarian tumor | 26 | |
| uterine tumor | 11 | |
|
| Developmental Stage | |
| Tissues | TPM* | |
|
| adult | 4 | |
| fetus | 1 | |
|
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
| |
|
| Expression level of Protein (ref. Human Protein Atlas) |
|
| |
|
| RNA-Seq. | |
| Tissues | FPKM | |
|
| appendix | 1.3 | |
| lymph node | 2 | |
| spleen | 2.6 | |
|
| Cancer | |
| Tumor | Number of patients and Staining levels | |
| breast cancer | |
| carcinoid | |
| cervical cancer | |
| colorectal cancer | |
| endometrial cancer | |
| glioma | |
| head and neck cancer | |
| liver cancer | |
| lung cancer | |
| lymphoma | |
| melanoma | |
| ovarian cancer | |
| pancreatic cancer | |
| prostate cancer | |
| renal cancer | |
| skin cancer | |
| stomach cancer | |
| testis cancer | |
| thyroid cancer | |
| urothelial cancer | |
|
| RNA-seq colour codes |
|
|
Highly expressed RNAs (FPKM >50) | |
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Moderately expressed RNAs (50> FPKM >10) | |
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Lower expressed RNAs (10> FPKM >1) | |
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The lowest expressed RNAs (FPKM value of 0 or 1) |
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| Staining level colour codes |
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Highly expressed protein | |
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Moderately expressed protein | |
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Lower expressed protein | |
|
Not Detected |
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> Protein (NX_Q6ZNE9)