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> Protein (NX_Q6ZT89)
Protein (NX_Q6ZT89)
Protein
Gene SymbolSLC25A48 to neXtProt (NX_Q6ZT89)
DescriptionSolute carrier family 25 member 48
Chromosome5
Location5q31.1 (135170338 ~ 135224326) to Ensembl
Sequene Features : Isoforms 3, Variants 48, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transmembrane transport .N/A .integral component of membrane
.mitochondrial inner membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
3 48 0
2014-09-19transcript level
3 35 0
2014-05-27transcript level
3 35 0
2014-02-25transcript level
3 35 0
2013-12-09transcript level
3 22 0
2013-11-01transcript level
3 22 0
2013-09-12transcript level
3 22 0
2013-08-17transcript level
3 22 0
2013-07-15transcript level
3 13 0
2013-06-11transcript level
3 13 0
2013-02-12transcript level
3 5 0
2012-12-20transcript level
3 10 0
2012-10-30transcript level
3 8 0
2012-10-07transcript level
3 8 0
2012-08-24transcript level
3 8 0
2012-07-28transcript level
3 8 0
2012-06-08transcript level
3 8 0
2012-05-07transcript level
3 8 0
2012-04-10transcript level
3 8 0
2012-01-13transcript level
3 7 0
2011-12-20transcript level
3 7 0
2011-11-11transcript level
3 7 0
2011-08-23transcript level
3 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6ZT89-1
6 10 0 33417.9515
NX_Q6ZT89-2
3 10 0 30940.5433
NX_Q6ZT89-3
1 7 0 16943.541
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10255185,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
2 EBI-10255185,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
3 EBI-10255185,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
4 EBI-10255185,EBI-1380492 UBASH3B  
  .negative regulation of platelet aggregation
.regulation of release of sequestered calcium ion into cytosol
.negative regulation of protein kinase activity
.protein tyrosine phosphatase activity .cytoplasm
.nucleus
5 EBI-10255185,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain3
connective tissue6
eye4
kidney14
Health State
TissuesTPM*
normal3
non-neoplasia10
Developmental Stage
TissuesTPM*
adult2
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
cerebral cortex12.9
colon1.7
duodenum1.4
kidney15.5
pancreas2.4
salivary gland1.5
skin1.7
small intestine3.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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