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> Protein (NX_Q6ZXV5)
Protein (NX_Q6ZXV5)
Protein
Gene SymbolTMTC3 to neXtProt (NX_Q6ZXV5)
DescriptionTransmembrane and TPR repeat-containing protein 3
Chromosome12
Location12q21.32 (88536073 ~ 88593664) to Ensembl
Sequene Features : Isoforms 2, Variants 94, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.bud outgrowth involved in lung branching
.muscle fiber development
.lung alveolus development
  + 2 more...
.N/A .integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 94 7
2014-09-19protein level
2 73 7
2014-05-27protein level
2 73 7
2014-02-25protein level
2 72 7
2013-12-09protein level
2 64 7
2013-11-01protein level
2 64 5
2013-09-12protein level
2 64 5
2013-08-17protein level
2 64 5
2013-07-15protein level
2 49 4
2013-06-11protein level
2 49 4
2013-02-12protein level
2 23 8
2012-12-20protein level
2 23 8
2012-10-30protein level
2 25 8
2012-10-07protein level
2 25 4
2012-08-24protein level
2 22 4
2012-07-28protein level
2 22 4
2012-06-08protein level
2 9 4
2012-05-07protein level
2 9 4
2012-04-10protein level
2 9 4
2012-01-13protein level
2 9 4
2011-12-20protein level
2 9 4
2011-11-11protein level
2 9 3
2011-08-23protein level
2 9 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q6ZXV5-1
0 37 1 103941.5952
NX_Q6ZXV5-2
0 37 1 103813.5007
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10188441,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder167
blood16
bone27
bone marrow20
brain5
connective tissue33
ear186
embryonic tissue23
eye14
intestine17
kidney85
liver24
lung26
mammary gland52
mouth15
muscle9
nerve64
pancreas9
placenta21
skin23
stomach10
testis34
trachea19
uterus21
vascular38
Health State
TissuesTPM*
normal20
bladder carcinoma113
breast (mammary gland) tumor10
chondrosarcoma60
colorectal tumor8
germ cell tumor30
glioma9
head and neck tumor7
kidney tumor29
leukemia10
liver tumor10
non-neoplasia31
primitive neuroectodermal tumor of the CNS7
skin tumor31
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult23
embryoid body28
blastocyst32
neonate32
fetus32
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.8
adrenal gland4.5
appendix4.4
bone marrow1.2
cerebral cortex4.8
colon5.1
duodenum5.1
esophagus9.7
gallbladder6.5
heart muscle3.1
kidney7.3
liver5.4
lung5.6
lymph node2.8
ovary5.2
pancreas1.4
placenta8.2
prostate7.3
salivary gland2.7
skin10.6
small intestine4.3
spleen3.5
stomach3.5
testis5.7
thyroid gland6.3
urinary bladder7.8
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowLow
breastLow
bronchusMedium
cerebral cortexMedium
cervix, uterineLow
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
esophagusMedium
fallopian tubeMedium
gallbladderLow
heart muscleLow
kidneyMedium
lateral ventricleMedium
lungMedium
nasopharynxMedium
oral mucosaMedium
pancreasMedium
parathyroid glandMedium
prostateMedium
rectumHigh
salivary glandLow
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
soft tissue 1Medium
soft tissue 2Medium
stomach 1High
stomach 2Medium
testisLow
tonsilHigh
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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