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> Protein (NX_Q70EK8)
Protein (NX_Q70EK8)
Protein
Gene SymbolUSP53 to neXtProt (NX_Q70EK8)
DescriptionInactive ubiquitin carboxyl-terminal hydrolase 53
Chromosome4
Location4q26 (120133742 ~ 120216672) to Ensembl
Sequene Features : Isoforms 1, Variants 111, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ubiquitin-dependent protein catabolic process .ubiquitinyl hydrolase activity .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 111 0
2014-09-19protein level
1 87 0
2014-05-27transcript level
1 87 0
2014-02-25transcript level
1 84 0
2013-12-09transcript level
1 56 0
2013-11-01transcript level
1 56 0
2013-09-12transcript level
1 56 0
2013-08-17transcript level
1 56 0
2013-07-15transcript level
1 35 0
2013-06-11transcript level
1 35 0
2013-02-12transcript level
1 21 0
2012-12-20transcript level
1 17 0
2012-10-30transcript level
1 27 0
2012-10-07transcript level
1 27 0
2012-08-24transcript level
1 26 0
2012-07-28transcript level
1 26 0
2012-06-08transcript level
1 32 0
2012-05-07transcript level
1 25 0
2012-04-10transcript level
1 25 0
2012-01-13transcript level
1 17 0
2011-12-20transcript level
1 17 0
2011-11-11transcript level
1 17 0
2011-08-23transcript level
1 17 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q70EK8-1
56 0 0 120729.7082
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
bladder33
bone13
bone marrow61
brain13
connective tissue20
embryonic tissue23
esophagus49
eye28
heart11
intestine17
kidney28
liver34
lung17
lymph node22
mammary gland72
mouth45
muscle37
pancreas9
parathyroid97
placenta35
prostate10
skin42
stomach41
testis32
thymus12
thyroid21
trachea19
uterus30
vascular135
Health State
TissuesTPM*
normal31
bladder carcinoma56
breast (mammary gland) tumor21
chondrosarcoma12
colorectal tumor17
esophageal tumor57
gastrointestinal tumor33
germ cell tumor15
glioma18
head and neck tumor7
kidney tumor29
leukemia31
liver tumor10
non-neoplasia51
pancreatic tumor9
skin tumor31
uterine tumor55
Developmental Stage
TissuesTPM*
adult30
embryoid body14
blastocyst48
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue42.3
adrenal gland20.2
appendix10
bone marrow1.2
cerebral cortex7.3
colon27.9
duodenum8.1
esophagus23.9
gallbladder16.3
heart muscle23.9
kidney23.1
liver6.1
lung19
lymph node18.4
ovary12
pancreas18
placenta13.7
prostate13.7
salivary gland14.2
skin11.1
small intestine11.2
spleen11.9
stomach18.3
testis12
thyroid gland8.7
urinary bladder17.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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