Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q70Z53)
Protein (NX_Q70Z53)
Protein
Gene SymbolFRA10AC1 to neXtProt (NX_Q70Z53)
DescriptionProtein FRA10AC1
Chromosome10
Location10q23.33 (95427640 ~ 95462329) to Ensembl
Sequene Features : Isoforms 5, Variants 42, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 42 8
2014-09-19protein level
5 38 8
2014-05-27protein level
5 38 8
2014-02-25protein level
5 38 8
2013-12-09protein level
5 32 8
2013-11-01protein level
5 31 7
2013-09-12protein level
5 31 7
2013-08-17protein level
5 31 7
2013-07-15protein level
5 21 6
2013-06-11protein level
5 21 6
2013-02-12protein level
5 10 28
2012-12-20protein level
5 11 28
2012-10-30protein level
5 13 28
2012-10-07protein level
5 13 8
2012-08-24protein level
5 12 8
2012-07-28protein level
5 12 8
2012-06-08protein level
5 4 8
2012-05-07protein level
5 4 8
2012-04-10protein level
5 4 8
2012-01-13protein level
5 4 8
2011-12-20protein level
5 10 8
2011-11-11protein level
5 10 8
2011-08-23protein level
5 10 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q70Z53-1
3 12 0 37524.5601
NX_Q70Z53-2
0 12 0 32875.5315
NX_Q70Z53-3
2 12 0 37462.0083
NX_Q70Z53-4
1 12 0 34752.4546
NX_Q70Z53-5
2 12 0 36895.4989
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-710176,EBI-710223 MAP3K12  
  .activation of mitophagy in response to mitochondrial depolarization
.protein autophosphorylation
.intracellular signal transduction
  + 5 more...
.protein homodimerization activity
.protein kinase binding
.ATP binding
  + 3 more...
.growth cone
.axon
.membrane
  + 3 more...
2 EBI-710176,EBI-713456 IK  
  .cell-cell signaling
.immune response
.identical protein binding .nucleolus
.nucleoplasm
.extracellular space
3 EBI-710176,EBI-749111 SF3B2  
  .viral process
.gene expression
.RNA splicing
  + 2 more...
.poly(A) RNA binding .catalytic step 2 spliceosome
.U12-type spliceosomal complex
.spliceosomal complex
.nucleoplasm
4 EBI-710176,EBI-2555370 CHERP  
  .positive regulation of NFAT protein import into nucleus
.release of sequestered calcium ion into cytosol
.negative regulation of cell proliferation
  + 3 more...
.poly(A) RNA binding
.ion channel binding
.perinuclear region of cytoplasm
.sarcoplasmic reticulum membrane
.membrane
.cytoplasm
5 EBI-710176,EBI-3928124 DGCR14  
  .nervous system development
.mRNA splicing, via spliceosome
.N/A .catalytic step 2 spliceosome
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
bladder33
bone13
brain17
connective tissue154
ear186
embryonic tissue42
eye52
kidney28
larynx85
liver9
lung29
lymph45
lymph node33
mammary gland6
muscle47
ovary49
pancreas18
parathyroid48
pituitary gland121
placenta17
prostate58
skin9
spleen37
stomach20
testis34
thymus12
thyroid21
umbilical cord72
uterus30
vascular38
Health State
TissuesTPM*
normal30
breast (mammary gland) tumor10
chondrosarcoma24
gastrointestinal tumor16
germ cell tumor3
glioma9
head and neck tumor22
kidney tumor14
liver tumor10
lymphoma41
non-neoplasia10
ovarian tumor26
pancreatic tumor19
primitive neuroectodermal tumor of the CNS15
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor199
uterine tumor22
Developmental Stage
TissuesTPM*
adult43
embryoid body42
blastocyst48
fetus21
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue20.7
adrenal gland19.6
appendix16.9
bone marrow8.5
cerebral cortex26.6
colon16.7
duodenum13.8
esophagus13.1
gallbladder16.4
heart muscle22.2
kidney18.4
liver10.7
lung18.1
lymph node21
ovary24.7
pancreas11.9
placenta13.4
prostate26.8
salivary gland22.1
skin21.7
small intestine14.4
spleen16.7
stomach17.7
testis26.5
thyroid gland23.4
urinary bladder19.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(+608866, gene/phenotype) Fragile site, folic acid-type, rare, fra(10)(q23.3), candidate geneOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2018 (C) Yonsei Proteome Research Center