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> Protein (NX_Q712K3)
Protein (NX_Q712K3)
Protein
Gene SymbolUBE2R2 to neXtProt (NX_Q712K3)
DescriptionUbiquitin-conjugating enzyme E2 R2
Chromosome9
Location9p13.3 (33817565 ~ 33920402) to Ensembl
Sequene Features : Isoforms 1, Variants 22, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein K48-linked ubiquitination
.proteasome-mediated ubiquitin-dependent protein catabolic process
.protein monoubiquitination
.ubiquitin conjugating enzyme activity
.ubiquitin protein ligase activity
.ubiquitin protein ligase binding
  + 4 more...
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 22 3
2014-09-19protein level
1 19 3
2014-05-27protein level
1 19 3
2014-02-25protein level
1 19 3
2013-12-09protein level
1 15 3
2013-11-01protein level
1 14 1
2013-09-12protein level
1 14 1
2013-08-17protein level
1 14 1
2013-07-15protein level
1 11 1
2013-06-11protein level
1 11 1
2013-02-12protein level
1 2 2
2012-12-20protein level
1 2 2
2012-10-30protein level
1 2 2
2012-10-07protein level
1 2 2
2012-08-24protein level
1 2 2
2012-07-28protein level
1 2 2
2012-06-08protein level
1 7 2
2012-05-07protein level
1 11 2
2012-04-10protein level
1 11 2
2012-01-13protein level
1 8 2
2011-12-20protein level
1 8 2
2011-11-11protein level
1 8 2
2011-08-23protein level
1 8 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q712K3-1
8 0 1 27148.9123
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2340879,EBI-2864512 MEOX1  
  .sclerotome development
.somite development
.hematopoietic stem cell differentiation
  + 2 more...
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.chromatin binding
  + 3 more...
.cytoplasm
.nucleus
2 EBI-2340879,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland30
ascites50
bladder33
blood89
bone167
bone marrow61
brain36
cervix41
connective tissue114
ear62
embryonic tissue89
eye90
heart212
intestine77
kidney90
larynx42
liver73
lung555
lymph67
lymph node155
mammary gland112
mouth151
muscle28
nerve64
ovary137
pancreas37
pharynx49
pituitary gland60
placenta45
prostate79
skin56
spleen18
stomach94
testis64
thymus12
thyroid21
tonsil58
umbilical cord145
uterus150
vascular77
Health State
TissuesTPM*
normal113
breast (mammary gland) tumor107
cervical tumor57
chondrosarcoma84
colorectal tumor97
gastrointestinal tumor109
germ cell tumor56
glioma65
head and neck tumor89
kidney tumor116
leukemia63
liver tumor93
lung tumor29
lymphoma110
non-neoplasia82
ovarian tumor144
pancreatic tumor38
primitive neuroectodermal tumor of the CNS55
prostate cancer48
retinoblastoma129
skin tumor31
soft tissue/muscle tissue tumor167
uterine tumor188
Developmental Stage
TissuesTPM*
adult178
embryoid body100
blastocyst65
neonate64
fetus70
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.5
adrenal gland20.4
appendix21.6
bone marrow10.6
cerebral cortex23.3
colon20.9
duodenum26.2
esophagus24.2
gallbladder24.7
heart muscle22.4
kidney19.8
liver19.8
lung16.9
lymph node23.9
ovary29.1
pancreas22.4
placenta25.1
prostate20
salivary gland10.7
skin22.8
small intestine23.7
spleen22.2
stomach20.8
testis39
thyroid gland22.5
urinary bladder26.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612506, gene) Ubiquitin-conjugating enzyme e2r 2; UBE2R2OMIM


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