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> Protein (NX_Q71RC2)
Protein (NX_Q71RC2)
Protein
Gene SymbolLARP4 to neXtProt (NX_Q71RC2)
DescriptionLa-related protein 4
Chromosome12
Location12q13.12 (50786166 ~ 50873787) to Ensembl
Sequene Features : Isoforms 7, Variants 83, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of cell morphogenesis
.cytoskeleton organization
.poly(A) RNA binding .membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
7 83 13
2014-09-19protein level
7 54 13
2014-05-27protein level
7 54 13
2014-02-25protein level
7 52 10
2013-12-09protein level
7 36 10
2013-11-01protein level
7 36 9
2013-09-12protein level
7 36 9
2013-08-17protein level
7 36 9
2013-07-15protein level
5 25 8
2013-06-11protein level
5 25 8
2013-02-12protein level
4 11 42
2012-12-20protein level
4 10 42
2012-10-30protein level
4 14 42
2012-10-07protein level
4 14 11
2012-08-24protein level
4 13 11
2012-07-28protein level
4 13 11
2012-06-08protein level
4 15 11
2012-05-07protein level
4 9 11
2012-04-10protein level
4 9 11
2012-01-13protein level
4 10 11
2011-12-20protein level
4 10 11
2011-11-11protein level
4 10 11
2011-08-23protein level
4 10 11
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q71RC2-1
0 30 0 80545.5832
NX_Q71RC2-2
1 24 0 67238.0615
NX_Q71RC2-3
0 30 0 80417.525
NX_Q71RC2-4
1 29 0 81192.9093
NX_Q71RC2-5
1 27 0 72354.5761
NX_Q71RC2-6
0 27 0 72687.8416
NX_Q71RC2-7
0 18 0 49920.1059
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10255841,EBI-711810 BHLHE40  
  .negative regulation of transcription, DNA-templated
.negative regulation of sequence-specific DNA binding transcription factor activity
.entrainment of circadian clock by photoperiod
  + 4 more...
.E-box binding
.protein heterodimerization activity
.MRF binding
  + 10 more...
.Golgi apparatus
.nucleolus
.nucleoplasm
.nucleus
2 EBI-10255841,EBI-748171 CRX  
  .retina development in camera-type eye
.response to stimulus
.positive regulation of photoreceptor cell differentiation
  + 5 more...
.leucine zipper domain binding
.nuclear hormone receptor binding
.sequence-specific DNA binding transcription factor activity
  + 3 more...
.transcription factor complex
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
bladder100
blood32
bone41
bone marrow61
brain20
cervix20
embryonic tissue46
esophagus49
eye43
heart22
intestine64
kidney123
larynx42
liver53
lung53
lymph22
lymph node200
mammary gland132
mouth30
muscle94
nerve128
ovary9
pancreas28
pharynx49
pituitary gland60
placenta38
prostate31
skin80
spleen18
stomach31
testis43
thyroid42
trachea57
uterus56
vascular58
Health State
TissuesTPM*
normal55
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor96
cervical tumor28
chondrosarcoma24
colorectal tumor79
esophageal tumor57
gastrointestinal tumor33
germ cell tumor68
glioma18
head and neck tumor37
kidney tumor116
leukemia31
liver tumor20
lung tumor9
lymphoma27
non-neoplasia10
pancreatic tumor19
primitive neuroectodermal tumor of the CNS15
prostate cancer48
retinoblastoma64
skin tumor47
soft tissue/muscle tissue tumor39
uterine tumor55
Developmental Stage
TissuesTPM*
adult47
embryoid body28
blastocyst81
fetus70
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue14.1
adrenal gland25.9
appendix16.4
bone marrow6.9
cerebral cortex9.6
colon14.5
duodenum14.9
esophagus17.1
gallbladder13.4
heart muscle12.2
kidney23.6
liver32.2
lung12
lymph node15.5
ovary8.6
pancreas7.5
placenta15.4
prostate13.6
salivary gland11.2
skin8.8
small intestine11.9
spleen10.7
stomach14.2
testis15.1
thyroid gland20.1
urinary bladder16.4
Tissues
TissuesExpression level
adrenal glandLow
appendixHigh
bone marrowHigh
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverHigh
lungMedium
lymph nodeMedium
nasopharynxHigh
oral mucosaHigh
ovaryLow
pancreasHigh
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
skeletal muscleLow
skin 1Low
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
spleenLow
stomach 1High
stomach 2High
testisMedium
thyroid glandLow
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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