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> Protein (NX_Q7L190)
Protein (NX_Q7L190)
Protein
Gene SymbolDPPA4 to neXtProt (NX_Q7L190)
DescriptionDevelopmental pluripotency-associated protein 4
Chromosome3
Location3q13.13 (109044988 ~ 109056419) to Ensembl
Sequene Features : Isoforms 1, Variants 77, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.lung-associated mesenchyme development
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 77 3
2014-09-19protein level
1 51 3
2014-05-27protein level
1 51 3
2014-02-25protein level
1 50 3
2013-12-09protein level
1 40 3
2013-11-01protein level
1 37 3
2013-09-12protein level
1 37 3
2013-08-17protein level
1 37 3
2013-07-15protein level
1 24 3
2013-06-11protein level
1 24 3
2013-02-12protein level
1 7 3
2012-12-20protein level
1 7 3
2012-10-30protein level
1 8 3
2012-10-07protein level
1 8 3
2012-08-24protein level
1 5 3
2012-07-28protein level
1 4 3
2012-06-08protein level
1 4 3
2012-05-07protein level
1 4 3
2012-04-10protein level
1 4 3
2012-01-13protein level
1 5 3
2011-12-20protein level
1 5 3
2011-11-11protein level
1 5 1
2011-08-23protein level
1 5 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q7L190-1
10 0 0 33519.5008
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-710457,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
2 EBI-710457,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
3 EBI-710457,EBI-73473 EIF4A2  
  .negative regulation of RNA-directed RNA polymerase activity
.cellular protein metabolic process
.cytokine-mediated signaling pathway
  + 8 more...
.poly(A) RNA binding
.ATPase activity
.ATP binding
  + 3 more...
.perinuclear region of cytoplasm
.eukaryotic translation initiation factor 4F complex
.cytosol
.nucleolus
4 EBI-710457,EBI-1050213 RPGRIP1  
  .retina development in camera-type eye
.response to stimulus
.eye photoreceptor cell development
.visual perception
.N/A .photoreceptor connecting cilium
.axoneme
5 EBI-710457,EBI-697911 SH3GL1  
  .central nervous system development
.signal transduction
.endocytosis
.identical protein binding
.lipid binding
.cell projection
.early endosome membrane
.cell junction
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone marrow41
brain1
embryonic tissue277
heart22
ovary9
placenta3
stomach20
testis91
thymus100
Health State
TissuesTPM*
normal22
germ cell tumor220
Developmental Stage
TissuesTPM*
adult26
embryoid body42
blastocyst764
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
bone marrow8.1
lymph node1.5
placenta3.7
testis7.3
Tissues
TissuesExpression level
appendixLow
bone marrowLow
breastLow
colonLow
heart muscleLow
hippocampusMedium
kidneyMedium
nasopharynxLow
oral mucosaLow
placentaMedium
rectumLow
skeletal muscleMedium
skin 2Low
small intestineLow
stomach 2Low
testisHigh
tonsilLow
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614125, gene) Developmental pluripotency-associated gene 4; DPPA4OMIM


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