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> Protein (NX_Q7L4I2)
Protein (NX_Q7L4I2)
Protein
Gene SymbolRSRC2 to neXtProt (NX_Q7L4I2)
DescriptionArginine/serine-rich coiled-coil protein 2
Chromosome12
Location12q24.31 (122989190 ~ 123011547) to Ensembl
Sequene Features : Isoforms 2, Variants 49, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .poly(A) RNA binding .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 49 13
2014-09-19protein level
2 36 13
2014-05-27protein level
2 35 13
2014-02-25protein level
2 35 13
2013-12-09protein level
2 30 13
2013-11-01protein level
2 29 13
2013-09-12protein level
2 29 13
2013-08-17protein level
2 29 13
2013-07-15protein level
2 21 13
2013-06-11protein level
2 21 13
2013-02-12protein level
2 8 21
2012-12-20protein level
2 8 21
2012-10-30protein level
2 9 21
2012-10-07protein level
2 9 14
2012-08-24protein level
2 3 14
2012-07-28protein level
2 3 14
2012-06-08protein level
2 4 14
2012-05-07protein level
2 4 14
2012-04-10protein level
2 4 14
2012-01-13protein level
2 2 14
2011-12-20protein level
2 2 14
2011-11-11protein level
2 2 13
2011-08-23protein level
2 2 13
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q7L4I2-1
2 9 0 50529.1474
NX_Q7L4I2-2
1 9 0 44851.2362
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10256202,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
2 EBI-10256202,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
3 EBI-10256202,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
4 EBI-10256202,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
5 EBI-10256202,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
6 EBI-10256202,EBI-2548702 CMTM5  
  .negative regulation of myoblast differentiation
.chemotaxis
.N/A .integral component of membrane
.extracellular space
7 EBI-10256202,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
8 EBI-10256202,EBI-741480 UBQLN1  
  .regulation of autophagic vacuole assembly
.positive regulation of ER-associated ubiquitin-dependent protein catabolic process
.regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
  + 8 more...
.identical protein binding
.polyubiquitin binding
.kinase binding
.perinuclear region of cytoplasm
.protein complex
.aggresome
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites75
bladder200
blood81
bone139
bone marrow82
brain71
cervix41
connective tissue80
ear186
embryonic tissue70
esophagus49
eye57
heart212
intestine51
kidney128
larynx42
liver116
lung125
lymph67
lymph node133
mammary gland52
mouth30
muscle65
nerve64
ovary29
pancreas28
parathyroid145
pharynx73
pituitary gland121
placenta144
prostate79
salivary gland148
skin23
spleen93
stomach31
testis55
thymus163
thyroid64
tonsil58
trachea38
umbilical cord72
uterus90
Health State
TissuesTPM*
normal96
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor53
cervical tumor57
chondrosarcoma132
colorectal tumor79
gastrointestinal tumor59
germ cell tumor72
glioma27
head and neck tumor44
kidney tumor101
leukemia105
liver tumor52
lung tumor38
lymphoma69
non-neoplasia62
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS70
prostate cancer48
retinoblastoma64
skin tumor7
soft tissue/muscle tissue tumor39
uterine tumor122
Developmental Stage
TissuesTPM*
adult81
embryoid body114
blastocyst65
neonate64
fetus114
infant85
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue43.4
adrenal gland57.3
appendix55
bone marrow279.5
cerebral cortex51.6
colon43.9
duodenum44.5
esophagus46.5
gallbladder53.3
heart muscle30.4
kidney46.5
liver33.4
lung51.7
lymph node66.8
ovary55.5
pancreas25.4
placenta57.7
prostate54.4
salivary gland34.8
skin46.7
small intestine47.8
spleen55.6
stomach48.5
testis57.7
thyroid gland53.9
urinary bladder46.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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