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> Protein (NX_Q7L4P6)
Protein (NX_Q7L4P6)
Protein
Gene SymbolBEND5 to neXtProt (NX_Q7L4P6)
DescriptionBEN domain-containing protein 5
Chromosome1
Location1p33 (49193195 ~ 49242641) to Ensembl
Sequene Features : Isoforms 2, Variants 53, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .Golgi apparatus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 53 1
2014-09-19protein level
2 40 1
2014-05-27protein level
2 40 1
2014-02-25protein level
2 40 1
2013-12-09protein level
2 36 1
2013-11-01protein level
2 34 1
2013-09-12protein level
2 34 1
2013-08-17protein level
2 34 1
2013-07-15protein level
2 17 1
2013-06-11protein level
2 17 1
2013-02-12protein level
2 8 1
2012-12-20protein level
2 7 1
2012-10-30protein level
2 8 1
2012-10-07protein level
2 8 1
2012-08-24protein level
2 4 1
2012-07-28protein level
2 4 1
2012-06-08protein level
2 5 1
2012-05-07protein level
2 5 1
2012-04-10protein level
2 5 1
2012-01-13protein level
2 3 1
2011-12-20protein level
2 3 1
2011-11-11protein level
2 3 1
2011-08-23protein level
2 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q7L4P6-1
10 14 0 48151.6021
NX_Q7L4P6-2
1 14 0 29197.033
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-724373,EBI-353818 EIF3D  
  .cellular protein metabolic process
.gene expression
.regulation of translational initiation
  + 4 more...
.poly(A) RNA binding
.translation initiation factor activity
.eukaryotic translation initiation factor 3 complex, eIF3m
.eukaryotic 48S preinitiation complex
.eukaryotic 43S preinitiation complex
  + 3 more...
2 EBI-724373,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
3 EBI-724373,EBI-3904603 BUD31  
  .regulation of transcription from RNA polymerase II promoter
.mRNA splicing, via spliceosome
.sequence-specific DNA binding transcription factor activity .spliceosomal complex
.nucleus
4 EBI-724373,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
5 EBI-724373,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
6 EBI-724373,EBI-10245913 LCE1B  
  .keratinization .N/A .N/A
7 EBI-724373,EBI-3439227 ZGPAT  
  .negative regulation of transcription, DNA-templated
.negative regulation of epidermal growth factor-activated receptor activity
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.nucleus
8 EBI-724373,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
9 EBI-724373,EBI-741945 VPS25  
  .membrane organization
.protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
.endosomal transport
  + 2 more...
.protein N-terminus binding
.protein homodimerization activity
.structural molecule activity
.extracellular exosome
.endosome membrane
.cytosol
  + 6 more...
10 EBI-724373,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
11 EBI-724373,EBI-2511991 USP20  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 4 more...
.zinc ion binding
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.G-protein coupled receptor binding
.perinuclear region of cytoplasm
.centrosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
brain10
connective tissue160
ear62
embryonic tissue18
esophagus49
eye33
heart67
larynx4133
lung17
lymph node33
pancreas9
parathyroid48
prostate10
spleen18
testis4
tonsil117
uterus4
Health State
TissuesTPM*
normal15
chondrosarcoma24
esophageal tumor57
germ cell tumor11
glioma18
head and neck tumor724
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
retinoblastoma21
soft tissue/muscle tissue tumor191
Developmental Stage
TissuesTPM*
adult68
blastocyst32
fetus41
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.7
adrenal gland6
appendix3.5
bone marrow1.8
cerebral cortex9.6
colon2.2
duodenum2.4
esophagus1.9
gallbladder6.8
heart muscle3.8
kidney9.7
lung3.5
lymph node8
ovary13.6
pancreas1.7
prostate4.4
salivary gland2.3
skin1.3
small intestine1.6
spleen8.9
stomach2.6
testis3.3
thyroid gland3.5
urinary bladder3.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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