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> Protein (NX_Q7L775)
Protein (NX_Q7L775)
Protein
Gene SymbolEPM2AIP1 to neXtProt (NX_Q7L775)
DescriptionEPM2A-interacting protein 1
Chromosome3
Location3p22.2 (37027357 ~ 37034795) to Ensembl
Sequene Features : Isoforms 1, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of glycogen (starch) synthase activity
.positive regulation of glycogen biosynthetic process
.response to insulin
.N/A .endoplasmic reticulum
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 44 4
2014-09-19protein level
1 30 4
2014-05-27protein level
1 30 4
2014-02-25protein level
1 30 4
2013-12-09protein level
1 26 4
2013-11-01protein level
1 26 2
2013-09-12protein level
1 26 2
2013-08-17protein level
1 26 2
2013-07-15protein level
1 18 2
2013-06-11protein level
1 18 2
2013-02-12protein level
1 3 1
2012-12-20protein level
1 3 1
2012-10-30protein level
1 5 1
2012-10-07protein level
1 5 1
2012-08-24protein level
1 5 1
2012-07-28protein level
1 5 1
2012-06-08protein level
1 8 1
2012-05-07protein level
1 8 1
2012-04-10protein level
1 8 1
2012-01-13protein level
1 6 1
2011-12-20protein level
1 6 1
2011-11-11protein level
1 6 1
2011-08-23protein level
1 6 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q7L775-1
22 0 0 70324.8713
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6255981,EBI-10176632 ZBTB14  
  .negative regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 2 more...
.cytoplasm
.nucleoplasm
.nucleus
2 EBI-6255981,EBI-351710 ACTN1  
  .regulation of nucleic acid-templated transcription
.actin crosslink formation
.negative regulation of cellular component movement
  + 8 more...
.ion channel binding
.ligand-dependent nuclear receptor transcription coactivator activity
.vinculin binding
  + 3 more...
.extracellular exosome
.dendritic spine
.cell projection
  + 14 more...
3 EBI-6255981,EBI-2932733 SERPINF1  
  .negative regulation of neuron death
.cellular response to dexamethasone stimulus
.cellular response to glucose stimulus
  + 19 more...
.serine-type endopeptidase inhibitor activity .extracellular exosome
.perinuclear region of cytoplasm
.axon hillock
  + 4 more...
4 EBI-6255981,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
5 EBI-6255981,EBI-741101 FHL3  
  .actin cytoskeleton organization
.muscle organ development
.zinc ion binding .Z disc
.focal adhesion
.nucleus
.stress fiber
6 EBI-6255981,EBI-2505861 TNFAIP1  
  .protein homooligomerization
.positive regulation of DNA replication
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 8 more...
.GTP-Rho binding .Cul3-RING ubiquitin ligase complex
.endosome
.cytoplasm
.nucleolus
7 EBI-6255981,EBI-9027502 KCTD1  
  .protein homooligomerization
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.transcription factor binding
.transcription corepressor activity
.nucleus
8 EBI-6255981,EBI-2799833 VPS52  
  .embryonic ectodermal digestive tract development
.protein transport
.ectodermal cell differentiation
.syntaxin binding .perinuclear region of cytoplasm
.endosome membrane
.Golgi apparatus
9 EBI-6255981,EBI-746909 CPSF7  
  .protein tetramerization
.mRNA 3'-end processing
.gene expression
  + 4 more...
.poly(A) RNA binding
.nucleotide binding
.membrane
.mRNA cleavage factor complex
.nucleoplasm
.nucleus
10 EBI-6255981,EBI-2874661 C1orf50  
  .N/A .N/A .N/A
11 EBI-6255981,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
12 EBI-6255981,EBI-745269 CCNB1IP1  
  .chiasma assembly
.protein ubiquitination
.spermatid development
  + 2 more...
.ubiquitin protein ligase activity
.ligase activity
.zinc ion binding
.nuclear lumen
.synaptonemal complex
13 EBI-6255981,EBI-739759 PRTFDC1  
  .nucleoside metabolic process .protein homodimerization activity
.magnesium ion binding
.nucleotide binding
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
blood32
bone83
bone marrow41
brain83
cervix20
connective tissue26
ear248
embryonic tissue46
eye38
heart78
intestine34
kidney56
larynx553
liver24
lung38
lymph node66
mammary gland52
mouth45
muscle65
nerve64
ovary29
pancreas23
parathyroid48
pituitary gland60
placenta45
prostate36
skin23
stomach20
testis45
thymus87
thyroid42
trachea115
uterus51
vascular58
Health State
TissuesTPM*
normal57
breast (mammary gland) tumor32
chondrosarcoma24
colorectal tumor35
gastrointestinal tumor16
germ cell tumor22
glioma65
head and neck tumor134
leukemia42
liver tumor10
non-neoplasia51
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS47
prostate cancer48
retinoblastoma43
skin tumor39
soft tissue/muscle tissue tumor47
uterine tumor22
Developmental Stage
TissuesTPM*
adult56
embryoid body57
blastocyst16
fetus78
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.1
adrenal gland10.9
appendix10.9
bone marrow7.6
cerebral cortex15
colon6.7
duodenum7.3
esophagus6.8
gallbladder8.1
heart muscle10.9
kidney8.7
liver5.8
lung9.2
lymph node12.5
ovary17.5
pancreas3.3
placenta6.7
prostate14.6
salivary gland6.7
skin8.3
small intestine7
spleen12.8
stomach7.7
testis8.6
thyroid gland21.5
urinary bladder7.4
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*607911, gene) Epm2a-interacting protein 1; EPM2AIP1OMIM


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