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> Protein (NX_Q7LBR1)
Protein (NX_Q7LBR1)
Protein
Gene SymbolCHMP1B to neXtProt (NX_Q7LBR1)
DescriptionCharged multivesicular body protein 1b
Chromosome18
Location18p11.21 (11851395 ~ 11854448) to Ensembl
Sequene Features : Isoforms 1, Variants 17, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of mitotic spindle assembly
.cell division
.establishment of protein localization
  + 7 more...
.protein domain specific binding .extracellular exosome
.late endosome membrane
.membrane coat
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 17 6
2014-09-19protein level
1 10 6
2014-05-27protein level
1 10 6
2014-02-25protein level
1 8 6
2013-12-09protein level
1 5 6
2013-11-01protein level
1 5 4
2013-09-12protein level
1 5 4
2013-08-17protein level
1 5 4
2013-07-15protein level
1 4 1
2013-06-11protein level
1 4 1
2013-02-12protein level
1 1 1
2012-12-20protein level
1 2 1
2012-10-30protein level
1 2 1
2012-10-07protein level
1 2 1
2012-08-24protein level
1 2 1
2012-07-28protein level
1 2 1
2012-06-08protein level
1 11 1
2012-05-07protein level
1 11 1
2012-04-10protein level
1 11 1
2012-01-13protein level
1 9 1
2011-12-20protein level
1 11 1
2011-11-11protein level
1 11 1
2011-08-23protein level
1 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q7LBR1-1
4 0 0 22095.1054
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2118090,EBI-396676 STAMBP  
  .negative regulation of Ras protein signal transduction
.negative regulation of neuron apoptotic process
.protein deubiquitination
  + 4 more...
.metal ion binding
.protein domain specific binding
.metallopeptidase activity
.ubiquitin-specific protease activity
.extracellular exosome
.cleavage furrow
.plasma membrane
  + 4 more...
2 EBI-2118090,EBI-1050865 USP8  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 6 more...
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.extrinsic component of endosome membrane
.midbody
.extrinsic component of plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bladder33
blood49
bone41
bone marrow20
brain28
cervix20
connective tissue33
ear186
embryonic tissue56
eye33
heart33
intestine43
kidney37
larynx42
liver63
lung47
lymph22
lymph node77
mammary gland26
mouth45
muscle37
nerve128
ovary78
pancreas79
parathyroid48
pituitary gland121
placenta70
prostate21
skin56
stomach73
testis20
thymus25
thyroid107
umbilical cord145
uterus64
vascular58
Health State
TissuesTPM*
normal44
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma48
colorectal tumor62
gastrointestinal tumor59
germ cell tumor18
glioma37
head and neck tumor59
kidney tumor14
leukemia84
liver tumor20
lung tumor29
lymphoma27
non-neoplasia20
ovarian tumor91
pancreatic tumor57
primitive neuroectodermal tumor of the CNS39
prostate cancer19
retinoblastoma86
skin tumor31
soft tissue/muscle tissue tumor39
uterine tumor44
Developmental Stage
TissuesTPM*
adult44
embryoid body28
blastocyst32
neonate128
fetus53
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue35.3
adrenal gland33
appendix33.2
bone marrow34.2
cerebral cortex27.9
colon38.3
duodenum33.4
esophagus37.9
gallbladder41.3
heart muscle26.5
kidney30.7
liver17.2
lung29.9
lymph node27.2
ovary27.2
pancreas11.4
placenta23.7
prostate28.3
salivary gland18.3
skin23
small intestine41.4
spleen28
stomach27
testis16.5
thyroid gland51.4
urinary bladder39.5
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusHigh
cerebellumLow
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleLow
hippocampusLow
kidneyMedium
lateral ventricleLow
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleLow
skeletal muscleLow
skin 1Medium
skin 2Low
small intestineHigh
soft tissue 1Medium
soft tissue 2Low
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606486, gene) Chmp family, member 1b; CHMP1BOMIM


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