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> Protein (NX_Q7Z3C6)
Protein (NX_Q7Z3C6)
Protein
Gene SymbolATG9A to neXtProt (NX_Q7Z3C6)
DescriptionAutophagy-related protein 9A
Chromosome2
Location2q35 (220074494 ~ 220094439) to Ensembl
Sequene Features : Isoforms 3, Variants 94, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.innate immune response
.late nucleophagy
.piecemeal microautophagy of nucleus
  + 5 more...
.N/A .recycling endosome
.late endosome membrane
.cytoplasmic vesicle
  + 8 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 94 11
2014-09-19protein level
3 66 11
2014-05-27protein level
3 64 11
2014-02-25protein level
3 64 11
2013-12-09protein level
3 37 11
2013-11-01protein level
3 36 10
2013-09-12protein level
3 36 9
2013-08-17protein level
3 36 9
2013-07-15protein level
3 16 8
2013-06-11protein level
3 16 8
2013-02-12protein level
3 9 17
2012-12-20protein level
3 13 17
2012-10-30protein level
3 21 17
2012-10-07protein level
3 21 8
2012-08-24protein level
3 18 8
2012-07-28protein level
3 17 8
2012-06-08protein level
3 24 8
2012-05-07protein level
3 25 8
2012-04-10protein level
3 25 8
2012-01-13protein level
3 26 8
2011-12-20protein level
3 26 8
2011-11-11protein level
3 26 8
2011-08-23protein level
3 26 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q7Z3C6-1
0 38 1 94386.7573
NX_Q7Z3C6-2
1 34 1 87323.4729
NX_Q7Z3C6-3
3 19 1 60654.1139
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-727146,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
2 EBI-727146,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
3 EBI-727146,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
4 EBI-727146,EBI-10175863 UBE3A  
  .regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.protein K48-linked ubiquitination
.prostate gland growth
  + 13 more...
.ubiquitin protein ligase activity
.metal ion binding
.ligase activity
  + 2 more...
.cytosol
.cytoplasm
.nucleus
.proteasome complex
5 EBI-727146,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
6 EBI-727146,EBI-2341787 LONRF1  
  .N/A .zinc ion binding
.ATP-dependent peptidase activity
.N/A
7 EBI-727146,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
8 EBI-727146,EBI-7568679 SUPT20H  
  .positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
.gastrulation
.autophagy
.chromatin organization
.transcription cofactor activity .SAGA-type complex
.nucleolus
.SAGA complex
9 EBI-727146,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
10 EBI-727146,EBI-356402 TBK1  
  .defense response to virus
.defense response to Gram-positive bacterium
.positive regulation of transcription from RNA polymerase II promoter
  + 20 more...
.phosphoprotein binding
.ATP binding
.protein serine/threonine kinase activity
  + 2 more...
.endosome membrane
.cytosol
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites100
bladder100
blood40
bone55
bone marrow20
brain190
cervix144
connective tissue40
embryonic tissue61
esophagus49
eye62
heart33
intestine51
kidney56
larynx170
liver53
lung83
lymph22
mammary gland66
mouth181
muscle84
nerve128
ovary118
pancreas51
pituitary gland121
placenta88
prostate73
salivary gland98
skin128
spleen56
stomach31
testis523
thymus150
thyroid42
trachea173
umbilical cord145
uterus68
vascular19
Health State
TissuesTPM*
normal100
bladder carcinoma170
breast (mammary gland) tumor96
cervical tumor57
chondrosarcoma108
colorectal tumor35
esophageal tumor57
gastrointestinal tumor84
germ cell tumor56
glioma93
head and neck tumor127
kidney tumor72
leukemia42
liver tumor93
lung tumor38
lymphoma13
non-neoplasia10
ovarian tumor144
pancreatic tumor104
primitive neuroectodermal tumor of the CNS149
prostate cancer105
retinoblastoma64
skin tumor183
soft tissue/muscle tissue tumor31
uterine tumor55
Developmental Stage
TissuesTPM*
adult64
embryoid body28
blastocyst81
neonate32
fetus87
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue23.7
adrenal gland18.4
appendix20.3
bone marrow26.3
cerebral cortex31.4
colon23.4
duodenum24.7
esophagus26.7
gallbladder22.6
heart muscle34.1
kidney20.6
liver13
lung23.7
lymph node19.6
ovary18.7
pancreas12.3
placenta31.1
prostate20.8
salivary gland16.6
skin27.8
small intestine25
spleen19.5
stomach19
testis67.2
thyroid gland19.2
urinary bladder20.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612204, gene) Autophagy 9, s. cerevisiae, homolog of, a; ATG9AOMIM


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