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> Protein (NX_Q7Z614)
Protein (NX_Q7Z614)
Protein
Gene SymbolSNX20 to neXtProt (NX_Q7Z614)
DescriptionSorting nexin-20
Chromosome16
Location16q12.1 (50700211 ~ 50715264) to Ensembl
Sequene Features : Isoforms 4, Variants 59, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein transport .phosphatidylinositol binding .endosome membrane
.plasma membrane
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 59 0
2014-09-19protein level
4 42 0
2014-05-27protein level
4 42 0
2014-02-25protein level
4 42 0
2013-12-09protein level
4 32 0
2013-11-01protein level
4 30 0
2013-09-12protein level
4 30 0
2013-08-17protein level
4 30 0
2013-07-15protein level
4 21 0
2013-06-11protein level
4 21 0
2013-02-12protein level
4 12 0
2012-12-20protein level
4 11 0
2012-10-30protein level
4 14 0
2012-10-07protein level
4 14 0
2012-08-24protein level
4 11 0
2012-07-28protein level
4 11 0
2012-06-08protein level
4 12 0
2012-05-07protein level
4 11 0
2012-04-10protein level
4 11 0
2012-01-13protein level
4 8 0
2011-12-20protein level
4 8 0
2011-11-11protein level
4 8 0
2011-08-23protein level
4 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q7Z614-1
8 5 0 36154.6678
NX_Q7Z614-2
1 5 0 17302.7072
NX_Q7Z614-3
2 4 0 14176.735
NX_Q7Z614-4
1 4 0 11124.37
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744896,EBI-3905054 ALAS1  
  .small molecule metabolic process
.cellular lipid metabolic process
.mitochondrion organization
  + 4 more...
.pyridoxal phosphate binding
.5-aminolevulinate synthase activity
.mitochondrial matrix
.mitochondrion
.cytoplasm
.nucleoplasm
2 EBI-744896,EBI-10178634 MAGEA11  
  .N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
3 EBI-744896,EBI-1030190 SELPLG  
  .cellular response to interleukin-6
.leukocyte adhesive activation
.leukocyte tethering or rolling
  + 3 more...
.receptor binding .integral component of membrane
.membrane
.integral component of plasma membrane
.plasma membrane
4 EBI-744896,EBI-740929 KLHL12  
  .negative regulation of canonical Wnt signaling pathway
.COPII vesicle coating
.Wnt signaling pathway
  + 2 more...
.N/A .Cul3-RING ubiquitin ligase complex
.ER to Golgi transport vesicle
.cytosol
.Golgi membrane
5 EBI-744896,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
6 EBI-744896,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
7 EBI-744896,EBI-2554984 TACC3  
  .regulation of cell cycle
.cytoplasmic sequestering of transcription factor
.regulation of microtubule-based process
  + 8 more...
.N/A .centrosome
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood8
bone marrow205
heart11
kidney9
lung2
lymph node311
mammary gland6
placenta14
spleen74
thymus276
uterus4
Health State
TissuesTPM*
normal19
breast (mammary gland) tumor10
germ cell tumor3
leukemia74
uterine tumor11
Developmental Stage
TissuesTPM*
adult3
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.2
adrenal gland1.2
appendix21.2
bone marrow9.9
colon2.6
duodenum2.4
esophagus1.9
gallbladder4.7
liver1.1
lung7.4
lymph node28.9
placenta2.4
prostate1
salivary gland1.5
skin2.2
small intestine3.3
spleen18.7
stomach4.6
urinary bladder8.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613281, gene) Sorting nexin 20; SNX20OMIM


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