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> Protein (NX_Q86SE5)
Protein (NX_Q86SE5)
Protein
Gene SymbolRALYL to neXtProt (NX_Q86SE5)
DescriptionRNA-binding Raly-like protein
Chromosome8
Location8q21.2 (85095022 ~ 85834079) to Ensembl
Sequene Features : Isoforms 3, Variants 68, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .poly(A) RNA binding
.identical protein binding
.nucleotide binding
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 68 1
2014-09-19protein level
3 50 1
2014-05-27protein level
3 50 2
2014-02-25protein level
2 47 2
2013-12-09protein level
2 42 2
2013-11-01protein level
2 41 2
2013-09-12protein level
2 41 2
2013-08-17protein level
2 41 2
2013-07-15protein level
2 27 1
2013-06-11protein level
2 27 1
2013-02-12transcript level
2 7 0
2012-12-20transcript level
2 10 0
2012-10-30transcript level
2 8 0
2012-10-07transcript level
2 8 0
2012-08-24transcript level
2 7 0
2012-07-28transcript level
2 7 0
2012-06-08transcript level
2 8 0
2012-05-07transcript level
2 6 0
2012-04-10transcript level
2 6 0
2012-01-13transcript level
2 2 0
2011-12-20transcript level
2 2 0
2011-11-11transcript level
2 2 0
2011-08-23protein level
2 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q86SE5-1
0 11 1 32310.4724
NX_Q86SE5-2
1 5 0 24773.5475
NX_Q86SE5-3
1 11 1 33890.3766
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741520,EBI-357966 HNRNPC  
  .3'-UTR-mediated mRNA stabilization
.ATP-dependent chromatin remodeling
.gene expression
  + 3 more...
.N6-methyladenosine-containing RNA binding
.poly(A) RNA binding
.identical protein binding
  + 7 more...
.catalytic step 2 spliceosome
.extracellular exosome
.protein complex
  + 6 more...
2 EBI-741520,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
3 EBI-741520,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
4 EBI-741520,EBI-740773 RBM41  
  .N/A .RNA binding
.nucleotide binding
.N/A
5 EBI-741520,EBI-741515 THAP1  
  .regulation of mitotic cell cycle
.cell cycle
.regulation of transcription, DNA-templated
  + 2 more...
.sequence-specific DNA binding
.identical protein binding
.zinc ion binding
.PML body
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain37
connective tissue33
kidney28
larynx42
lung17
muscle9
pancreas9
pituitary gland60
prostate5
vascular19
Health State
TissuesTPM*
normal18
head and neck tumor14
kidney tumor14
non-neoplasia10
prostate cancer9
soft tissue/muscle tissue tumor39
Developmental Stage
TissuesTPM*
adult10
fetus21
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland21.1
cerebral cortex29.9
gallbladder6.4
heart muscle2.4
kidney16.3
spleen2.5
Tissues
TissuesExpression level
adrenal glandHigh
cerebellumHigh
cerebral cortexHigh
colonHigh
epididymisLow
fallopian tubeLow
gallbladderHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
pancreasMedium
rectumLow
skin 2Low
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614648, gene) Raly-like protein; RALYLOMIM


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